Results 121 to 130 of about 2,342,845 (294)

Randomized comparison of in vivo performance of two point-of-care tear film osmometers

Clinical Ophthalmology, 2017
Jerry Nolfi, Barbara Caffery Toronto Eye Care Optometric Clinic, Toronto, ON, Canada Purpose: To compare the in vivo precision of two commercially available point-of-care osmometers among normal subjects with no dry eye disease. Methods: Twenty healthy
Nolfi J, Caffery B
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Protocol for the creation and characterization of SARS-CoV-2 variant testing panels using remnant clinical samples for diagnostic assay testing

STAR Protocols
Summary: The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Alpha variant in 2020 demonstrated the need for reanalysis of diagnostic tests to ensure detection of emerging variants.
Leda Bassit, Heather B. Bowers, Morgan Greenleaf, Courtney Sabino, Eric Lai, Grace Yu, Anne Piantadosi, Ethan Wang, William O’Sick, Kaleb McLendon, Julie A. Sullivan, Raymond F. Schinazi, Gregory L. Damhorst, Wilbur Lam, Anuradha Rao   +14 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Role Of Point Of Care Ultrasound In The Diagnosis Of Retinal Detachment In The Emergency Department

Open Access Emergency Medicine, 2019
Shadi Lahham,1 Qumber Ali,2 Bea Martina Palileo,3 Clifton Lee,3 John C Fox1 1University of California, Irvine, Department of Emergency Medicine, Orange, CA 92868, USA; 2Touro University, School of Medicine, Henderson, NV 89014, USA; 3University of ...
Lahham S, Ali Q, Palileo BM, Lee C, Fox JC   +4 more
doaj  

Toward diagnostic preparedness: detection of highly pathogenic avian influenza A(H5N1) in contrived nasal swab specimens using rapid antigen and point-of-care molecular tests

Journal of Clinical Microbiology
Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b was first detected in birds in 2021 in the United States (U.S.). An ongoing outbreak in dairy cattle began in early 2024 involving genotype B3.13. At least 70 U.S. cases have been identified
Leda Bassit, Gregory L. Damhorst, Heather B. Bowers, Courtney Sabino, Julie Sullivan, Emily B. Kennedy, Jacob Khouri, Pamela Miller, Eric Lai, Raymond F. Schinazi, Wilbur A. Lam, Nira R. Pollock, Anuradha Rao   +12 more
doaj   +1 more source

International evidence-based recommendations for point-of-care lung ultrasound

Intensive Care Medicine, 2012
G. Volpicelli, M. Elbarbary, M. Blaivas, D. Lichtenstein, G. Mathis, A. Kirkpatrick, L. Melniker, L. Gargani, V. Noble, G. Via, A. Dean, J. Tsung, G. Soldati, R. Copetti, B. Bouhemad, A. Reissig, E. Agricola, J. Rouby, C. Arbelot, A. Liteplo, A. Sargsyan, Fernando R Silva, R. Hoppmann, R. Breitkreutz, A. Seibel, L. Neri, E. Storti, T. Petrovic, International Liaison Committee on Lung Ultrasound for the Inter Ultrasound   +28 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Obstetric Point of Care Echocardiography

Kansas Journal of Medicine, 2022
Harrington, Ross P., Babiash, Kimberly
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source