Results 151 to 160 of about 2,053,462 (244)

Integration of Point-of-Care Ultrasound Training into Undergraduate Medical Curricula—A Perspective from Medical Students

Journal of Medical Education and Curricular Development, 2016
Jasmine Y. Fu, Cassie Krause, Reed Krause, Josh McCoy, April Schindler, Daniel S. Udrea, Logan A. Villarreal, Zan Jafry, Vi Am Dinh   +8 more
doaj  

Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection. [PDF]

Cochrane Database Syst Rev
Dinnes J, Berhane S, Walsh J, Reidy P, Doherty A, Hillier B, Scandrett K, Hettiarachchi D, Islam F, Mathangasinghe Y, Nyaaba N, Taylor M, Weeratunga P, Wickramasinghe D, van Wyk SS, Cunningham J, Davenport C, Dittrich S, Emperador D, Hooft L, Leeflang MM, McInnes MD, Spijker R, Verbakel JY, Takwoingi Y, Taylor-Phillips S, Van den Bruel A, Deeks JJ, Cochrane COVID-19 Diagnostic Test Accuracy Group.   +28 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Accurate Point-of-Care Detection of Ruptured Fetal Membranes: Improved Diagnostic Performance Characteristics with a Monoclonal/Polyclonal Immunoassay

Clinical Medicine Insights: Reproductive Health, 2016
Linda C. Rogers, Laurie Scott, Jon E. Block   +2 more
doaj  

Point-of-care ultrasonography in Turkish primary care: a qualitative exploration of practice and experience. [PDF]

BMC Prim Care
Odabaş ÖK, Başer DA, Özkara A.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Neonatal point-of-care ultrasound-steps for program development. [PDF]

J Perinatol
Bhombal S, Singh Y, Marshall S, Mukthapuram S, Fraga MV, National Neonatal POCUS Collaborative.   +5 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Academic Point-of-Care Manufacturing in Oral and Maxillofacial Surgery: A Retrospective Review at Gregorio Marañón University Hospital. [PDF]

Medicina (Kaunas)
Tousidonis M, Ruiz-de-Leon G, Navarro-Cuellar C, Ochandiano S, Salmeron JI, Franco Herrera R, Calvo-Haro JA, Perez-Mañanes R.   +7 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source