Results 111 to 120 of about 1,493,527 (373)

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Accuracy of point-of-care SARS-CoV-2 detection using buccal swabs in pediatric emergency departments

open access: yesMicrobiology Spectrum
To optimize the identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected children, specimen collection and testing method are crucial considerations.
Stephen B. Freedman   +19 more
doaj   +1 more source

Clinical measurements obtained from point-of-care ultrasound images to assess acquisition skills

open access: yesThe Ultrasound Journal, 2019
Background Current methods of assessing competence in acquiring point-of-care ultrasound images are inadequate. They rely upon cumbersome rating systems that do not depend on the actual outcome measured and lack evidence of validity.
Brian P. Lucas   +5 more
doaj   +1 more source

Integral equivalence of multidimensional differential systems [PDF]

open access: yesarXiv, 2009
The bases of the theory of integrals for multidimensional differential systems are stated. The integral equivalence of total differential systems, linear homogeneous systems of partial differential equations, and Pfaff systems of equations is established.
arxiv  

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

open access: yesMolecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen   +6 more
wiley   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

Fractional Multidimensional System [PDF]

open access: yesarXiv, 2017
The multidimensional ($n$-D) systems described by Roesser model are presented in this paper. These $n$-D systems consist of discrete systems and continuous fractional order systems with fractional order $\nu$, $0<\nu<1$. The stability and Robust stability of such $n$-D systems are investigated.
arxiv  

Point-of-care testing in diabetes management

open access: yesRomanian Journal of Laboratory Medicine, 2019
The prevalence of diabetes mellitus (DM) has rapidly increased over the last decades, reaching epidemic magnitudes, particularly in lowand middle-income countries. Point-of-care (POC) technology enables decision making near or at the site of patient care.
Cozma Angela   +3 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

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