Results 71 to 80 of about 1,493,527 (373)

An integrated and automated electronic system for point-of-care protein testing [PDF]

open access: yes2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019
Protein testing in blood is important for clinical analysis. Traditional blood tests are performed in centralized laboratories and are slow to provide results. In contrast, point-of-care devices deliver rapid results in non-laboratory settings, allowing timely analysis and in turn reducing healthcare costs.
Wu, Dan, Voldman, Joel
openaire   +4 more sources

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

Informatics-based product-service systems for point-of-care devices [PDF]

open access: yesCIRP Journal of Manufacturing Science and Technology, 2010
Informatics related to point-of-care devices denotes the ability to translate stand-alone biological data into meaningful information that can be interpreted to enable and support users in taking the most appropriate steps to aid in managing their health.
Adeogun, Oluseun   +2 more
openaire   +5 more sources

Application of scoring systems with point-of-care ultrasonography for bedside diagnosis of appendicitis.

open access: yesWorld Journal of Emergency Medicine, 2016
BACKGROUND Appendicitis is a common disease requiring surgery. Bedside ultrasound (BUS) is a core technique for emergency medicine (EM). The Alvarado score is a well-studied diagnostic tool for appendicitis.
E. E. Ünlüer   +7 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Electrochemical SARS-CoV-2 Sensing at Point-of-Care and Artificial Intelligence for Intelligent COVID-19 Management

open access: yesACS Applied Bio Materials, 2020
To manage the COVID-19 pandemic, development of rapid, selective, sensitive diagnostic systems for early stage β-coronavirus severe acute respiratory syndrome (SARS-CoV-2) virus protein detection is emerging as a necessary response to generate the ...
A. Kaushik   +6 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Equivariant Filter Design for Kinematic Systems on Lie Groups [PDF]

open access: yesarXiv, 2020
It is known that invariance and equivariance properties for systems on Lie groups can be exploited in the design of high performance and robust observers and filters for real-world robotic systems. This paper proposes an analysis framework that allows any kinematic system on a Lie group to be embedded in a natural manner into an equivariant kinematic ...
arxiv  

A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems [PDF]

open access: yesScientific Reports, 2017
AbstractCardio-respiratory monitoring is one of the most demanding areas in the rapidly growing, mobile-device, based health care delivery. We developed a 12-lead smartphone-based electrocardiogram (ECG) acquisition and monitoring system (called “cvrPhone”), and an application to assess underlying ischemia, and estimate the respiration rate (RR) and ...
Eric M. Isselbacher   +10 more
openaire   +5 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

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