The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings.
WHO has proposed a public-health approach to antiretroviral therapy (ART) to enable scaling-up access to treatment for HIV-positive people in developing countries, recognising that the western model of specialist physician management and advanced ...
Crowley, Siobhan+9 more
core +1 more source
Canadian Journey to a National Electronic Health Record [PDF]
Report detailing Canada's journey towards its national EHR. Canada has chosen to utilise hub-and-spoke repositories over point-to-point information exchange systems.
Rimpilainen, Sanna
core +1 more source
A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems [PDF]
AbstractCardio-respiratory monitoring is one of the most demanding areas in the rapidly growing, mobile-device, based health care delivery. We developed a 12-lead smartphone-based electrocardiogram (ECG) acquisition and monitoring system (called “cvrPhone”), and an application to assess underlying ischemia, and estimate the respiration rate (RR) and ...
Eric M. Isselbacher+10 more
openaire +5 more sources
Infection Models for Pine Wilt Disease on the Basis of Vector Behaviors
Infection models for pine wilt disease without vector density were built to estimate the transmission coefficient of the pathogenic nematode. The models successfully simulated the annual change in the density of infected trees for four pine stands. ABSTRACT Pine wilt disease is caused by the pinewood nematode (Bursaphelenchus xylophilus Steiner et ...
Katsumi Togashi
wiley +1 more source
The best of both worlds : how primary care can save lives and money [PDF]
Just imagine, for a moment, that you receive a request from a newly independent country, anywhere in the world, appointing you to devise a health care system. You have an absolutely free hand to design it as you wish. Where would you start?
Haslam, David
core
Spatial accessibility and social inclusion: The impact of Portugal's last health reform [PDF]
Health policies seek to promote access to health care and should provide appropriate geographical accessibility to each demographical functional group.
Ben‐Akiva M. E.+12 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Willingness to Pay for Community Health Fund Card in Mtwara Rural District,Tanzania [PDF]
\ud The Ministry of Health in Tanzania has established a new programme in the primary health care service. CHF is a district-level prepayment scheme targeted at the rural population.CHF starts in 1995 on a pilot basis in one district and in 2003 has to ...
Baraldes, Carme, Carreras , Lluis
core
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source