Results 81 to 90 of about 1,493,527 (373)

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Prevalence of Cryptococcal Antigenemia and Lateral Flow Assay Accuracy in Severely Immunosuppressed AIDS Patients

Journal of Fungi
This study aimed to estimate the prevalence of cryptococcal antigenemia detected by lateral flow assay (LFA) in AIDS patients and its accuracy in the diagnosis of cryptococcosis.
Adriana Carla Garcia Negri, Maína de Oliveira Nunes, Gláucia Moreira Espíndola Lima, James Venturini, Sandra Maria do Valle Leone de Oliveira, Márcia dos Santos Lazera, Lídia Raquel de Carvalho, Marilene Rodrigues Chang, Rosianne Assis de Sousa Tsujisaki, Adriana de Oliveira França, Rinaldo Poncio Mendes, Anamaria Mello Miranda Paniago   +11 more
doaj   +1 more source

Classical and Point-of-Care tests in severe hemorrhage management

AboutOpen, 2022
 Hemorrhage is defined as an acute loss of blood from the cardiovascular system. The hemostatic cascade (comprising the vasculature, coagulation factors, the fibrinolytic and the platelet systems) is the physiological mechanism meant to control this ...
Paolo Simioni
doaj   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Enhancing implementation of a standardized initial assessment for demand management in outpatient emergency care in Germany: a quantitative process evaluation

BMC Medical Informatics and Decision Making, 2021
Background Inadequate assessment of the severity and urgency of health problems is one of the factors contributing to unnecessary emergency department visits.
Amanda Breckner, Catharina Roth, Joachim Szecsenyi, Michel Wensing   +3 more
doaj   +1 more source

Point-of-Care Testing: Administration Within a Health System [PDF]

Laboratory Medicine, 2000
Point-of-care testing (POCT) is spreading throughout health care systems in the United States. This article outlines an administrative structure for establishing and managing a POCT program in a health care system and discusses the role of the POCT coordinator in maintaining a quality assurance and training program that meets all the regulatory ...
Frederick L. Kiechle, Rhonda Ingram Main
openaire   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Compact integral manifolds of differential systems [PDF]

arXiv, 2010
The boundedness tests for the number of compact integral manifolds of autonomous ordinary differential systems, of autonomous total differential systems, of linear systems of partial differential equations, of Pfaff systems of equations, and of systems of exterior differential equations are proved.
arxiv  

Using Structure-Behavior Coalescence Method for Systems Definition 2.0 [PDF]

arXiv, 2021
Systems definition is an artifact created by humans to describe what a system is. A system has been defined, by systems definition 1.0, hopefully to be an integrated whole, embodied in its components, their interrelationships with each other and the environment, and the principles and guidelines governing its design and evolution.
arxiv  

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source