Results 91 to 100 of about 20,182,406 (278)
Jamming Transition of Point-to-Point Traffic Through Cooperative Mechanisms
We study the jamming transition of two-dimensional point-to-point traffic through cooperative mechanisms using computer simulation. We propose two decentralized cooperative mechanisms which are incorporated into the point-to-point traffic models ...
Huang D. +5 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
River Notes: A Natural and Human History of the Colorado
Review of River Notes: A Natural and Human History of the Colorado. Wade Davis. 2012. Island Press. Pp. 176 $23.63 (Hardcover). ISBN 978‐1610913614.
Thomas W. La Point
doaj +1 more source
The feminine in Buddhism [PDF]
The following is a report of a one-day conference held at Providence Zen Center in June, 1983 on "The Feminine in Zen Buddhism." This and the Naropa Institute conferences of the previous two summers have been among the few public forums to focus on ...
Primary Point
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Pédagogie universitaire et numérique : le défi d’une éthique de l’attention
Christophe Point
doaj +1 more source

