Results 101 to 110 of about 20,182,406 (278)
Undergraduate students learn about mammalian cell culture applications in introductory biology courses. However, laboratory modules are rarely designed to provide hands-on experience with mammalian cells or teach cell culture techniques, such as ...
Kristen Bowey-Dellinger +12 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Student-Designed High-Throughput Assays to Assess Effects of Growth Insults in Budding Yeast
Modern high-throughput screening is a versatile method used widely in academic and industrial labs for genetic and pharmacological testing, but is underutilized in undergraduate laboratories.
Veronica A. Segarra +6 more
doaj +1 more source
Expansion schemes for gravitational clustering: computing two-point and three-point functions
We describe various expansion schemes that can be used to study gravitational clustering. Obtained from the equations of motion or their path-integral formulation, they provide several perturbative expansions that are organized in different fashion or ...
Berges +35 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Understanding Fixed Point Theorems [PDF]
Fixed point theorems are the standard tool used to prove the existence of equilibria in mathematical economics. This paper shows how to prove a slight generalization of Brouwer's and Kakutani's fixed point theorems using the familiar techniques of ...
Arnold, Lutz G.
core
Point-Map-Probabilities of a Point Process and Mecke's Invariant Measure Equation
A compatible point-shift $F$ maps, in a translation invariant way, each point of a stationary point process $\Phi$ to some point of $\Phi$. It is fully determined by its associated point-map, $f$, which gives the image of the origin by $F$. It was proved
Baccelli, François +1 more
core +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

