The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi +11 more
wiley +1 more source
3D perception algorithm of unstructured environment based on point cloud enhanced pixel fusion. [PDF]
Chen G, Wan L, He J, Jiang S, Song L.
europepmc +1 more source
The SPG‐MpECis electrochemical POCT platform developed in this study enables direct detection of biomarkers in complex biological samples such as serum and fingerstick blood, demonstrating high concordance with results from clinical reference methods and holding broad potential for at‐home testing applications.
Menghan Li +10 more
wiley +1 more source
A strengthened soft-point registration network for LiDAR point cloud registration. [PDF]
Chen Y +6 more
europepmc +1 more source
A dynamic Ag+─S coordinated hydrogel with a sulfur–oxygen competitive coordination allosteric switch enables reversible tuning between soft–adhesive and stiff–robust states. Integrated with a lightweight 1DCNN classifier, the smart glove system achieves 99.70% laboratory and 93.35% real‐wear material recognition accuracy, offering a paradigm for self ...
Shixia Lan +4 more
wiley +1 more source
tgLang: A Domain-Specific Language for Geometry Processing and Computational Imaging Workflows. [PDF]
Suriyababu VK, Vuik C, Möller M.
europepmc +1 more source
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou +12 more
wiley +1 more source
A Multi-Dimensional Vision-Based System for External Thread Defect Detection with Integrated Security Defense. [PDF]
Li L, Zhang G.
europepmc +1 more source
PA-DFNet: Polarity-Aware Attention Network with Feature Dynamic Fusion for Point Cloud Classification and Semantic Segmentation. [PDF]
Su Z, Jin K, Hao J, Han B.
europepmc +1 more source
An Embedded Multi-Sensor IoT Platform for Agricultural Monitoring Using Meshtastic-Based LoRa Communication and Cloud Microservices. [PDF]
Negulescu C +3 more
europepmc +1 more source

