Results 51 to 60 of about 6,640,887 (230)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Robust estimation in simultaneous equations models [PDF]

open access: yes, 1994
In this paper we review existing work on robust estimation for simultaneous equations models. Then we discuss three strategies for obtaining estimators with a high breakdown point, a controllable efficiency, and a reasonable computational cost: (a ...
Yohai, Víctor J., Maronna, Ricardo A.
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

NormNet: Point-wise normal estimation network for three-dimensional point cloud data

open access: yesInternational Journal of Advanced Robotic Systems, 2019
In this article, a point-wise normal estimation network for three-dimensional point cloud data called NormNet is proposed. We propose the multiscale K-nearest neighbor convolution module for strengthened local feature extraction.
Janghun Hyeon   +3 more
doaj   +1 more source

Real-time pose estimation of underground unmanned aerial vehicle based on ICP method

open access: yesGong-kuang zidonghua, 2019
In view of characteristics of no GPS signal, low illumination and structured environment in coal mine, a real-time pose estimation method for underground unmanned aerial vehicle (UAV) based on iterative closest point (ICP) was proposed.
WANG Yan   +3 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Categorical Variable Segmentation Model for Software Development Effort Estimation

open access: yesIEEE Access, 2019
This paper proposes a new software development effort estimation model. The new model's design is based on the function point analysis, categorical variable segmentation (CVS), and stepwise regression.
Petr Silhavy   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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