Results 61 to 70 of about 355,686 (307)

Markov chain Monte Carlo methods for state-space models with point process observations [PDF]

, 2012
This letter considers how a number of modern Markov chain Monte Carlo (MCMC) methods can be applied for parameter estimation and inference in state-space models with point process observations.
Niranjan, Mahesan, Girolami, Mark, Yuan, Ke   +2 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Autoencoder Architectures for Low-Rate Sparse Point Cloud Geometry Coding

IEEE Access
Efficient compression of sparse point cloud geometry remains a critical challenge in 3D content processing, particularly for low-rate scenarios where conventional codecs struggle to maintain efficiency. This work proposes a system-level framework for low-
Ivaylo Bozhilov, Radostina Petkova, Krasimir Tonchev, Agata Manolova, Vladimir Poulkov, H. Vincent Poor   +5 more
doaj   +1 more source

Matrix geometries emergent from a point [PDF]

Reviews in Mathematical Physics, 2014
We describe a categorical approach to finite noncommutative geometries. Objects in the category are spectral triples, rather than unitary equivalence classes as in other approaches. This enables us to treat fluctuations of the metric and unitary equivalences on the same footing, as representatives of particular morphisms in this category. We then show
D'ANDREA, FRANCESCO, LIZZI, FEDELE, Pierre Martinetti   +2 more
openaire   +4 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

EXPERIMENTS WITH UAS IMAGERY FOR AUTOMATIC MODELING OF POWER LINE 3D GEOMETRY [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
The ideal mapping technology for transmission line inspection is the airborne LiDAR executed from helicopter platforms. It allows for full 3D geometry extraction in highly automated manner.
G. Jóźków, B. Vander Jagt, C. Toth
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Developments in noncommutative differential geometry [PDF]

, 2002
One of the great outstanding problems of theoretical physics is the quantisation of gravity, and an associated description of quantum spacetime. It is often argued that, at short distances, the manifold structure of spacetime breaks down and is replaced ...
Hale, Mark
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

BuildingComSSSM: Building point cloud completion with Geometry-Aware Mambas

International Journal of Applied Earth Observations and Geoinformation
Building point cloud completion facilitates the geometry model reconstruction. Existing transformer-based completion methods have achieved competitive performance by generating dense point clouds from sparse inputs.
Huchen Li, Cheng Wang, Haibing Liu, Yang Ming, Fei Deng, Wufan Zhao   +5 more
doaj   +1 more source