Results 41 to 50 of about 72,833 (270)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The effect of non-standard loading platen usage on point load index value of rocks
, 2021 The point load index is a simple, fast, and inexpensive method for determining rock strength and can be applied both in the field and in the laboratory.
Altındağ, Raşit, Akbay, Deniz
core +1 more source
Correlation between uniaxial compressive strength and point load strength of Penang Island Granites [PDF]
, 2022 Uniaxial compressive strength (UCS) is one of the most widely used strength parameters in geotechnical design. The value is obtained through direct testing method, carried out through careful procedures of testing in a laboratory setting.
Mat Said, K. N. +5 more
core +1 more source
INVESTIGATING THE ANISOTROPY STRENGTH INDEX (ASI) FOR SOME EGYPTIAN ORNAMENTAL STONES
Rudarsko-geološko-naftni Zbornik, 2023 The nature of ornamental stones is anisotropic. The heterogeneous characteristics of the anisotropic rocks vary with direction. The highest to lowest strength ratio is known as the anisotropy strength index (ASI).
Ahmed M. Shohda +4 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2019 The damage index is a crucial controlling parameter for rock mass strength and deformation in civil, geological and mining engineering projects. In this study, a new method was proposed for computing the damage index of a rock mass based on the field ...
Wen, Lei +5 more
core +1 more source
Journal of Rock Mechanics and Geotechnical Engineering, 2020 The uniaxial compressive strength (UCS) of rock is an important parameter required for design and analysis of rock structures, and rock mass classification. Uniaxial compression test is the direct method to obtain the UCS values. However, these tests are
Adeyemi Emman Aladejare
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Shock and Vibration, 2021 To investigate the strength characteristics of mudstone in deep-buried coal-measure formation, four types of experiments have been conducted: (i) the X-ray diffraction (XRD) test; (ii) the scanning electron microscope (SEM) scanning test; (iii) the point
Ke Li +6 more
doaj +1 more source