Results 111 to 120 of about 5,667,138 (292)
Pavee Point annual report 2003-2005 [PDF]
Introduction to Pavee Point Pavee Point is a national Traveller organisation whose staff and participants are Travellers and members of the majority population working together in partnership to address Travellers social and economic exclusion.
Pavee Point Travellers Centre
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Point Mutations in the α -Synuclein Gene
Idiopathic Parkinson's disease (PD) is an age-dependent, neurodegenerative disorder and is predominantly sporadic. Only 20-30% of patients have a positive family history for PD with a complex mode of inheritance. In a few extended families, the disease is inherited as an autosomal dominant trait.
A, Parsian, J S, Perlmutter
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Taqman-MGB nanoPCR for Highly Specific Detection of Single-Base Mutations
Zhenrui Xue,1– 3,* Minli You,2,3,* Ping Peng,1– 3,* Haoyang Tong,2,3 Wanghong He,2– 4 Ang Li,4 Ping Mao,1– 3 Ting Xu,1 Feng Xu,2,3 Chunyan Yao1 1Department of Transfusion Medicine, Southwest Hospital, Third Military Medical ...
Xue Z +9 more
doaj
Nitrogen-to-Carbon Single Atom Point Mutation of Pyridine N-Oxides [PDF]
Single-atom editing has emerged as a powerful process for altering molecular structures with precision. Within this growing class of transformations, reactions that replace one atom for another in heterocycles, while desirable, remain limited.
Erik, Sorensen +4 more
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Central Point Notice of Adopted Amendment (2008-05-19)
14 pp. Adopted 2008-05-19. Department of Land Conservation and Development Notice of Adopted AmendmentThe attached approved amendment is the updated population and demographic element of the City of Central Point Comprehensive Plan.
Central Point (Or.)
core +1 more source
Central Point Notice of Adopted Amendment (2011-04-29)
65 pp. Adopted 2011-04-29. Department of Land Conservation and Development Notice of Adopted AmendmentRevision to the Flood Damage Prevention ordinance to make the revised Federal Emergency Management Agency (FEMA) Flood Insurance Rate Map (FIRM) panels ...
Central Point (Or.)
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

