Results 1 to 10 of about 41,122 (231)

The Effect of Cytochrome P450 and Organic Anion Transporter Polypeptide on Macrolides–Atorvastatin Drug Interaction

Iraqi Journal of Industrial Research
Cytochrome P450 (CYP3A4) enzymes and organic anion-transporting polypeptides (OATPs) are critical in drug pharmacokinetics. Fifteen rabbits were divided into three groups: the atorvastatin group received a single oral dose of atorvastatin (0.86 mg/kg B ...
Zainab Farooq Abdalhameed, Orooba Mohammed Saeed Ibrahim   +1 more
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Mutations in the 23S rRNA gene are associated with clarithromycin resistance in Helicobacter pylori isolates in Brazil

Annals of Clinical Microbiology and Antimicrobials, 2003
Background Resistance of Helicobacter pylori to clarithromycin has been associated with A2142G and A2143G point mutations in the 23S rRNA gene. Thus, the purpose of the present study was to determine the prevalence of each mutation in 52 clarithromycin ...
Godoy Anita PO, Benvengo Yune HB, Miranda Maira CB, Vitiello Lea, Ribeiro Marcelo L, Mendonca Sergio, Pedrazzoli José   +6 more
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Role of MIC levels and 23S rRNA mutation sites to clarithromycin in 14-day clarithromycin bismuth quadruple therapy for Helicobacter pylori eradication: A prospective trial in Beijing

Heliyon
Background: Rising clarithromycin resistance undermines Helicobacter pylori (H. pylori) treatment efficacy. We aimed to determine clarithromycin's minimum inhibitory concentration (MIC) levels and identify specific mutation sites in the 23S ribosomal ...
Ying Chen, Siyu Li, Wenbin Li, Yiran Wang, Jihua Shi, Xue Xu, Pan Zhang, Dan Chen, Rui Gang, Qingfeng Luo   +9 more
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Detection of antimicrobial resistance genes of Helicobacter pylori strains to clarithromycin, metronidazole, amoxicillin and tetracycline among Egyptian patients

Egyptian Journal of Medical Human Genetics, 2018
Background: Antibiotic resistance of Helicobacter pylori (H. pylori) treatment is on the rise, and is affecting the efficacy of current used therapeutic regimens. Aim: We aimed to enhance the understanding of antimicrobial resistance rates of H.
Manal Diab, Ahmed El-Shenawy, Maged El-Ghannam, Dalia Salem, Moustafa Abdelnasser, Mohamed Shaheen, Mahmoud Abdel-Hady, Effat El-Sherbini, Mohamed Saber   +8 more
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Clarithromycin in early pregnancy and the risk of miscarriage and malformation: a register based nationwide cohort study. [PDF]

PLoS ONE, 2013
BACKGROUND: The antibiotic clarithromycin has been associated with fetal loss in animals and a study has found a doubling in the frequency of miscarriages among women using clarithromycin in pregnancy.
Jon Trærup Andersen, Morten Petersen, Espen Jimenez-Solem, Espen Jimenez-Solem, Kasper Broedbaek, Nadia Lyhne Andersen, Christian Torp-Pedersen, Niels Keiding, Henrik Enghusen Poulsen   +8 more
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The study of mutation in 23S rRNA resistance gene of Helicobacter pylori to clarithromycin in patients with gastrointestinal disorders in Isfahan - Iran

Advanced Biomedical Research, 2014
Background: Helicobacter pylori antimicrobial resistance is an important factor responsible for treatment failure. The purpose of this study was evaluating the prevalence of point mutations in clarithromycin-resistant clinical isolates of H.
Farzad Khademi, Jamshid Faghri, Sharareh Moghim, Bahram Nasr Esfahani, Hossein Fazeli, Farkhondeh Poursina, Peyman Adibi, Masoumeh Madhi, Hajieh Ghasemian Safaei   +8 more
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General Soil Properties Modulate Bacterial Community Tolerance to Clarithromycin in Laboratory-Spiked Agricultural Soils

Agriculture
Clarithromycin is a widely prescribed macrolide antibiotic that can enter soils using sewage treatment plant effluents, where it is frequently detected.
Laura Rodríguez-González, Manuel Arias-Estévez, Montserrat Díaz-Raviña, Juan José Villaverde, David Fernández-Calviño, Vanesa Santás-Miguel   +5 more
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Antimicrobial resistance of Helicobacter pylori strains to five antibiotics, including levofloxacin, in Northwestern Turkey

Revista da Sociedade Brasileira de Medicina Tropical, 2015
INTRODUCTION: Antibiotic resistance is the main factor that affects the efficacy of current therapeutic regimens against Helicobacter pylori. This study aimed to determine the rates of resistance to efficacy clarithromycin, amoxicillin, tetracycline ...
Reyhan Caliskan, Hrisi Bahar Tokman, Yusuf Erzin, Suat Saribas, Pelin Yuksel, Bora Kazim Bolek, Ecehan Ozge Sevuk, Mehmet Demirci, Ozge Yılmazli, Ozer Akgul, Fatma Kalayci, Huseyin Cakan, Barik Salih, Kadir Bal, Bekir Kocazeybek   +14 more
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Efflux Pumps Contribute to Intrinsic Clarithromycin Resistance in Clinical, Mycobacterium abscessus Isolates

Infection and Drug Resistance, 2020
Qi Guo,1,2 Jianhui Chen,1,2 Shaoyan Zhang,1 Yuzhen Zou,1,2 Yongjie Zhang,1,2 Dongdong Huang,1 Zhemin Zhang,1 Bing Li,1 Haiqing Chu1,3 1Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433,
Guo Q, Chen J, Zhang S, Zou Y, Zhang Y, Huang D, Zhang Z, Li B, Chu H   +8 more
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Rapid detection of clarithromycin-resistant Helicobacter pylori in patients with dyspepsia by fluorescent in situ hybridization (FISH) compared with the E-test

Annals of Saudi Medicine, 2007
Background: Clarithromycin is the antibiotic of choice for treatment of H. pylori-related dyspepsia, but unfortunately, resistance to clarithromycin is not rare. Detection of resistant strains takes 2 to 4 days by conventional methods. In this report, we
Moosavian Mojtaba, Tajbakhsh Saeid, Samarbaf-Zadeh Ali   +2 more
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