Results 31 to 40 of about 40,048 (221)

Polymorphism of virulence genes and biofilm associated with in vitro induced resistance to clarithromycin in Helicobacter pylori

open access: yesGut Pathogens, 2023
Background Clarithromycin-containing triple therapy is commonly used to treat Helicobacter pylori infections. Clarithromycin resistance is the leading cause of H. pylori treatment failure. Understanding the specific mutations that occur in H.
Naim Asyraf Rosli   +5 more
doaj   +1 more source

In Vitro Comparison Of Clarithromycin, Clarithromycin plus 14-Hydroxy Clarithromycin, and Azithromycin Against Haemophilus influenzae [PDF]

open access: yes, 1998
The antibiotic activities of clarithromycin, clarithromycin plus 14-hydroxy clarithromycin and azithromycin against Haemophilus influenzae were compared.
Arnold, Amy
core   +1 more source

Lack of association between rrl and erm(41) mutations and clarithromycin resistance in Mycobacterium abscessus complex

open access: yesMemorias do Instituto Oswaldo Cruz
BACKGROUND Mycobacterium abscessus complex (MABC) includes species with high resistance rates among mycobacterial pathogens. In fact, MABC infections may not respond to clarithromycin treatment, which has historically been very effective against MABC ...
Maiara dos Santos Carneiro   +3 more
doaj   +1 more source

Detection of A2142C, A2142G, and A2143G Mutations in 23s rRNA Gene Conferring Resistance to Clarithromycin among Helicobacter pylori Isolates in Kerman, Iran [PDF]

open access: yesIranian Journal of Medical Sciences, 2011
Background: Clarithromycin resistance in Helicbacter pylori has been found to be associated with point mutations in 23s rRNA gene leads to reduced affinity of the antibiotic to its ribosomal target or changing the site of methylation.
Hamid Abdollahi   +4 more
doaj  

Influence of clarithromycin on the bactericidal effect of amoxicillin in patients infected with clarithromycin-resistant strains of H. pylori [PDF]

open access: yes, 2020
Suzuki et al. reported that the VA-Dual therapy was better at eradicating the clarithromycin-resistant strains of H. pylori than the VAC-Triple therapy.
Higuchi, Tomohiro   +11 more
core   +2 more sources

The effect of mild and moderate hepatic impairment on the pharmacokinetics, safety and tolerability of balcinrenone

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson   +8 more
wiley   +1 more source

Clarithromycin-resistant Helicobacter pylori in Recife, Brazil, directly identified from gastric biopsies by polymerase chain reaction

open access: yesArquivos de Gastroenterologia, 2010
CONTEXT: Clarithromycin is the most effective drug used in the eradication of infection by Helicobacter pylori. Due to worldwide increase in resistance, pre-treatment susceptibility testing for clarithromycin is recommended.
Ana Kelly Lins   +2 more
doaj   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed   +7 more
wiley   +1 more source

Clarithromycin-Induced Digoxin Intoxication

open access: yes, 1997
Objective To report a case of clarithromycin-induced digoxin intoxication. Case Summary A 78-year-old white man with ischemic cardiomyopathy and chronic renal insufficiency was admitted 4 days after being prescribed clarithromycin for a suspected episode
Patrice Laberge, Pierre Martineau
core   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

open access: yesBMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang   +6 more
wiley   +1 more source

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