Antibiotic Susceptibility and Clarithromycin Resistance Determinants in Helicobacter pylori in the Northeast of Spain: A One-Year Prospective Study [PDF]
Antibiotics, 2023 Helicobacter pylori is one of the most widespread infections, and it is reaching alarming resistance levels worldwide. The recommended first-line empirical treatment differs according to the local rate of clarithromycin resistance.
Saray Mormeneo Bayo +9 more
doaj +2 more sources
Pathophysiology of Antibiotic Resistance: Clarithromycin [PDF]
Canadian Journal of Gastroenterology & Hepatology, 2000 Resistance ofHelicobacter pylorito antibiotics ranges from 3% to 10% and may exceed these levels in some countries. The pathophysiology of clarithromycin resistance is reviewed, including the mode of action by which the antibiotic inhibits protein synthesis and the mechanism of resistance, which involves a mutation at position 2142 or 2143 in the V ...
Diane E Taylor, D E Taylor
exaly +5 more sources
Molecular Characterization of Clarithromycin Resistance in Helicobacter pylori Strains. [PDF]
Turk J Gastroenterol, 2023 Background: The purpose of this study was to determine the antimicrobial status of stocked clinical Helicobacter pylori isolates by using antibiotic gradient test and subsequently identify the mutations that cause clarithromycin resistance by DNA sequencing.
Örsten S, Yılmaz E, Akyön Y.
europepmc +4 more sources
Genetic Evolution of Mycobacterium abscessus Conferring Clarithromycin Resistance during Long-Term Antibiotic Therapy [PDF]
Canadian Respiratory Journal, 2020 Objectives. Clarithromycin is recommended as the core agent for treating M. abscessus infections, which usually calls for at least one year of treatment course, facilitating the development of resistance.
Bing Li +6 more
doaj +2 more sources
Genetic basis of clarithromycin resistance in Bacillus anthracis. [PDF]
Microbiol SpectrABSTRACT The high-consequence pathogen Bacillus anthracis causes human anthrax and often results in lethal infections without the rapid administration of effective antimicrobial treatment.
Maxson T +9 more
europepmc +4 more sources
Early genetic diagnosis of clarithromycin resistance in Helicobacter pylori. [PDF]
World J Gastroenterol, 2021 The drug resistance rate of clinical Helicobacter pylori (H. pylori) isolates has increased. However, the mechanism of drug resistance remains unclear. In this study, drug-resistant H. pylori strains were isolated from different areas and different populations of Chinese for genomic analysis.To investigate drug-resistant genes in H. pylori and find the
Li XH +9 more
europepmc +3 more sources
Clarithromycin Resistance in Helicobacter Pylori
Central Asian Journal of Medical Sciences, 2016 Objectives: Eradication rates of Helicobacter pylori with standard triple therapy are disappointing in studies from several countries. The main reason for failure was found to be bacterial resistance to one of the most commonly used antibiotics ...
Mandkhai Bolor-Erdene +2 more
doaj +2 more sources
Inducible and Acquired Clarithromycin Resistance in the Mycobacterium abscessus Complex.
PLoS ONE, 2015 PurposeClarithromycin was considered the cornerstone for the treatment of Mycobacterium abscessus complex infections. Genetic resistance mechanisms have been described and many experts propose amikacin as an alternative.
Marc Rubio +5 more
doaj +5 more sources
Clinical utility of fecal Sanger sequencing and PCR alongside gastric biopsy E-test for Helicobacter pylori resistance to clarithromycin and quinolone [PDF]
Microbiology SpectrumTo guide Helicobacter pylori eradication, we determined the prevalence and predictability of clarithromycin and quinolone resistance in 277 consecutive culture-positive patients who underwent gastroscopy.
Juan Xu +6 more
doaj +2 more sources
Clinical analysis of the resistance of Helicobacter pylori to commonly prescribed antibiotics in Chinese mainland [PDF]
Jichu yixue yu linchuang, 2022 Objective To find the trends and regional differences of the resistance of Helicobacter pylori(Hp) to metronidazole, clarithromycin, levofloxacin, amoxicillin, furazolidone and tetracycline in recent years in the mainland of China.
ZHAO Xia, XU Wei-wei, LIU Yi-meng, SUO Zhi-min
doaj +1 more source