Results 21 to 30 of about 18,197 (177)

Effect of plaunotol in combination with clarithromycin against clarithromycin-resistant Helicobacter pylori in vitro and in vivo [PDF]

Journal of Antimicrobial Chemotherapy, 2007
Recently, there has been a decrease in the eradication rate of Helicobacter pylori due to the increase in antibiotic resistance of this bacterium. Plaunotol, a cytoprotective anti-ulcer agent, exhibits antibacterial activity against H. pylori. The purpose of the present study was to investigate the effect of plaunotol in combination with clarithromycin
Makoto, Sasaki, Tsutomu, Mizoshita, Takashi, Mizushima, Harumi, Inoue, Takeshi, Kamiya, Hiromi, Kataoka, Naotaka, Ogaswara, Tsuneya, Wada, Eiji, Kubota, Yoshinori, Mori, Takaya, Shimura, Hirokazu, Hirata, Kenji, Ando, Yasuyuki, Okamoto, Hirotaka, Ohara, Haruhisa, Nakao, Takashi, Joh   +16 more
openaire   +2 more sources

Impact of Helicobacter pylori resistance to clarithromycin on the efficacy of the omeprazole–amoxicillin–clarithromycin therapy [PDF]

Alimentary Pharmacology & Therapeutics, 2001
Background: Helicobacter pylori resistance to clarithromycin is relatively frequent in France and is assumed to be the main cause of failure of the proton pump inhibitor–amoxicillin–clarithromycin (proton pump inhibitor–AC) therapy, which is the first‐line regimen in France.Aim:To determine the respective effects of clarithromycin primary and secondary
J, Tankovic, D, Lamarque, C, Lascols, C J, Soussy, J C, Delchier   +4 more
openaire   +2 more sources

Clarithromycin-Resistant Mycobacterium avium Is Still Susceptible to Treatment with Clarithromycin and Is Virulent in Mice [PDF]

Antimicrobial Agents and Chemotherapy, 2000
ABSTRACT Resistance to clarithromycin in breakthrough Mycobacterium avium complex (MAC) isolates typically occurs 3 to 4 months after the initiation of monotherapy in bacteremic AIDS patients. It has been suggested that continuation of clarithromycin therapy still results in clinical and microbiological ...
L E, Bermudez, K, Nash, M, Petrofsky, L S, Young, C B, Inderlied   +4 more
openaire   +2 more sources

Antibiotic resistance of Helicobacter pylori isolated from patients in Nanjing, China: A cross-section study from 2018 to 2021

Frontiers in Cellular and Infection Microbiology, 2022
The increasing antibiotic resistance of Helicobacter pylori infection is a globally urging problem. To investigate the H. pylori resistance situation in Nanjing, China, we enrolled patients in Nanjing First Hospital from January 2018 to May 2021.
Zongdan Jiang, Xuetian Qian, Zhi Wang, Yunfan Dong, Yuqin Pan, Zhenyu Zhang, Shukui Wang   +6 more
doaj   +1 more source

Assessment of antimycobacterial activities of pure compounds extracted from Thai medicinal plants against clarithromycin-resistant Mycobacterium abscessus [PDF]

PeerJ, 2021
Background Infection with Mycobacterium abscessus is usually chronic and is associated with clarithromycin resistance. Increasing drug resistance is a major public-health problem and has led to the search for new antimycobacterial agents.
Auttawit Sirichoat, Irin Kham-ngam, Orawee Kaewprasert, Pimjai Ananta, Awat Wisetsai, Ratsami Lekphrom, Kiatichai Faksri   +6 more
doaj   +2 more sources

Clarithromycin-resistant Helicobacter pylori in Recife, Brazil, directly identified from gastric biopsies by polymerase chain reaction

Arquivos de Gastroenterologia, 2010
CONTEXT: Clarithromycin is the most effective drug used in the eradication of infection by Helicobacter pylori. Due to worldwide increase in resistance, pre-treatment susceptibility testing for clarithromycin is recommended.
Ana Kelly Lins, Roberto A Lima, Marcelo Magalhães   +2 more
doaj   +1 more source

Clarithromycin resistance and 23S rRNA gene point mutations of Helicobacter pylori infection in children

The Turkish Journal of Pediatrics, 2016
This study aims to evaluate Helicobacter pylori with clarithromycin resistant genotypes in Manisa region, Turkey. Two hundred patients, who received diagnosis of Helicobacter pylori infection histopathologically, were included.
Yeliz Çağan-Appak, Hörü Gazi, Semin Ayhan, Beyhan Cengiz-Özyurt, Semra Kurutepe, Erhun Kasırga   +5 more
doaj   +1 more source

Clinical Resistance of Helicobacter pylori and Its Trend: A 10-year Data Analysis at Peking University People's Hospital

Xiehe Yixue Zazhi, 2023
Objective  To study the resistance of Helicobacter pylori(Hp) isolated from Peking University People's Hospital to commonly used antibiotics, in order to provide basis for clinical rational drug use.
ZHANG Feifei, WANG Qi, LI Shuguang, WANG Zhanwei, LIANG Xinyue, MENG Han, YANG Shuo, WANG Hui   +7 more
doaj   +1 more source

Detection of A2142C, A2142G, and A2143G Mutations in 23s rRNA Gene Conferring Resistance to Clarithromycin among Helicobacter pylori Isolates in Kerman, Iran [PDF]

Iranian Journal of Medical Sciences, 2011
Background: Clarithromycin resistance in Helicbacter pylori has been found to be associated with point mutations in 23s rRNA gene leads to reduced affinity of the antibiotic to its ribosomal target or changing the site of methylation.
Hamid Abdollahi, Mohammad Savari, Mohammad Javad Zahed, Sodaif Darvish Moghadam, Mehdi Hayatbakhsh Abasi   +4 more
doaj  

Genotypic and Phenotypic Resistance to Clarithromycin in Helicobacter pylori Strains [PDF]

Journal of Clinical Medicine, 2020
Background: The increasing prevalence of antimicrobial resistance, together with the lack of novel treatment options, negatively affects successful eradication of Helicobacter pylori. The aim of this study was to investigate genetic mutations in the 23S rRNA genes, which is associated with clarithromycin resistance, and to determine the clinical impact
Eun Jeong Gong, Ji Yong Ahn, Jung Mogg Kim, Sun Mi Lee, Hee Kyong Na, Jeong Hoon Lee, Kee Wook Jung, Kee Don Choi, Do Hoon Kim, Ho June Song, Gin Hyug Lee, So Won Kim, Hwoon-Yong Jung   +12 more
openaire   +2 more sources