CONTEXT: Clarithromycin is the most effective drug used in the eradication of infection by Helicobacter pylori. Due to worldwide increase in resistance, pre-treatment susceptibility testing for clarithromycin is recommended.
Ana Kelly Lins +2 more
doaj +1 more source
Objective To study the resistance of Helicobacter pylori(Hp) isolated from Peking University People's Hospital to commonly used antibiotics, in order to provide basis for clinical rational drug use.
ZHANG Feifei +7 more
doaj +1 more source
Detection of A2142C, A2142G, and A2143G Mutations in 23s rRNA Gene Conferring Resistance to Clarithromycin among Helicobacter pylori Isolates in Kerman, Iran [PDF]
Background: Clarithromycin resistance in Helicbacter pylori has been found to be associated with point mutations in 23s rRNA gene leads to reduced affinity of the antibiotic to its ribosomal target or changing the site of methylation.
Hamid Abdollahi +4 more
doaj
Rapid screening of clarithromycin resistance in Helicobacter pylori by pyrosequencing [PDF]
Helicobacter pylori infections can be effectively treated with clarithromycin, a macrolide, in combination with other antibiotics, such as amoxicillin, tetracycline or metronidazole. The failure of H. pylori eradication is mainly associated with macrolide-resistant strains.
Karen-Anja, Moder +3 more
openaire +2 more sources
In The Netherlands, both an increase in and regional differences in erythromycin resistance of Campylobacter jejuni and Campylobacter coli have been reported.
Claas, E.C.J. +19 more
core +1 more source
Safety and tolerability of clarithromycin in the treatment of multidrug-resistant tuberculosis [PDF]
Clarithromycin had a good tolerability and safety profile as assessed in MDR-TB patients receiving prolonged treatment http://ow.ly ...
Anne-Fleur Louise Van der Paardt +14 more
openaire +3 more sources
Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population [PDF]
Background: In Iran, there is insufficient information on the efficacy of Helicobacter pylori eradication regimens shorter than 10 days. This study aims at assessing the efficacy of 4- and 7-day H. pylori eradication regimens in a high-incidence area of
میکاییلی, جواد +15 more
core +1 more source
Clinical Whole Genome Sequencing for Clarithromycin and Amikacin Resistance Prediction and Subspecies Identification of Mycobacterium abscessus. [PDF]
Mycobacterium abscessus infections are an emerging health care concern in patients with chronic pulmonary diseases, leading to high morbidity and mortality. One major challenge is resistance to clarithromycin, a cornerstone antibiotic with high efficacy.
Mirasol, Ruel +3 more
core +1 more source
Susceptibility-Guided Versus Empirical Therapy for Helicobacter pylori Infection in a High Resistance Setting: A Randomised Controlled Trial. [PDF]
In a randomised trial conducted in a high‐resistance region, PCR‐based susceptibility‐guided therapy showed no superiority over empirical therapy for Helicobacter pylori eradication. Empirical clarithromycin‐containing quadruple therapy remained effective despite high clarithromycin resistance.
Lu K +11 more
europepmc +2 more sources
Clarithromycin overcomes resistance to lenalidomide and dexamethasone in multiple myeloma [PDF]
The combination of clarithromycin, lenalidomide and dexamethasone (BiRd) has led to highly durable responses in newly diagnosed myeloma. However, the ability of clarithromycin to overcome resistance to lenalidomide and dexamethasone (Rd) is not known.
Nilanjan, Ghosh +5 more
openaire +2 more sources

