Results 61 to 70 of about 20,556 (211)

Antimicrobial Resistance Molecular Mechanisms of Helicobacter pylori in Jordanian Children: A Cross-Sectional Observational Study

Antibiotics, 2023
Background: H. pylori antimicrobial resistance causes increasing treatment failure rates among H. pylori gastritis in children. This study investigates the molecular mechanisms of H. pylori antimicrobial resistance among Jordanian children.
Salma Burayzat, Mohammad Al-Tamimi, Mohammad Barqawi, Mustafa Sabri Massadi, Jumanah Abu-Raideh, Hadeel Albalawi, Ashraf I. Khasawneh, Nisreen Himsawi, Maha Barber   +8 more
doaj   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Antibiotic resistance and associated gene mutations of Helicobacter pylori in children: a three-year retrospective study in Shanghai, China

Frontiers in Cellular and Infection Microbiology
BackgroundThe changes in the antibiotic resistance patterns of Helicobacter pylori (H. pylori) are critical for guiding clinical eradication therapy. However, data on antibiotic resistance in H. pylori strains isolated from children in Shanghai have been
Chunling Li, Yonghui Lu, Keyue Zhu, Leiyan He, Pan Fu, Pan Fu, Saige Chen, Jie Qin, Ying Huang, Chuanqing Wang, Chuanqing Wang   +10 more
doaj   +1 more source

The antibiotic resistance of Helicobacter pylori to five antibiotics and influencing factors in an area of China with a high risk of gastric cancer

BMC Microbiology, 2019
Background H. pylori exhibits antibiotic resistance with regional differences. In this paper, we explored antibiotic resistance of H. pylori to five antibiotics in an area with a high risk of gastric cancer. Results H.
Dan Wang, Qianqian Guo, Yuan Yuan, Yuehua Gong   +3 more
doaj   +1 more source

A Novel Reduction Strategy of Clarithromycin Resistance in Helicobacter pylori [PDF]

Jundishapur Journal of Microbiology, 2014
Antibiotic resistance is a major therapeutic problem in patients infected with Helicobacter pylori. H. pylori clarithromycin resistant mutants have been evolved during antibiotic therapy, this is mainly due to 23s rRNA point mutations.In the present study, we investigated anti-mutational features of four traditionally Iranian medicinal plants on three ...
Tadjrobehkar, Omid, Abdollahi, Hamid
openaire   +2 more sources

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Advance in Helicobacter pylori resistance to clarithromycin

World Chinese Journal of Digestology, 2008
Helicobacter pylori (H pylori) infection is the main cause of chronic active gastritis and peptic ulcer disease, and studies indicated eradication of H pylori could promote the healing of peptic ulcer. H pylori resistance to clarithromycin, which shows an increasing tendency year by year, is related with mutations of H pylori 23S rRNA domain V ...
Shi-Hai Xuan, Yu-Gui Zhou, Hui-Min Wang
openaire   +1 more source

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

Clarithromycin Resistance and Eradication of Helicobacter pylori in Children [PDF]

Antimicrobial Agents and Chemotherapy, 2001
ABSTRACT Outcome of Helicobacter pylori infection was analyzed in 61 children treated with a triple therapy including clarithromycin. Bacterial eradication was obtained in all children with clarithromycin-susceptible strains but not in children with clarithromycin-resistant ones ( P
N, Kalach, P H, Benhamou, F, Campeotto, M, Bergeret, C, Dupont, J, Raymond   +5 more
openaire   +2 more sources

Cystitis in guinea pigs (Cavia porcellus): Clinical findings and treatment outcomes

Veterinary Record, EarlyView.
Abstract Background This retrospective study examined the incidence, diagnostic methods, bacterial isolates, treatments and outcomes associated with cystitis in guinea pigs presented at a single clinic between 2009 and 2022. Methods The clinic's medical records database was reviewed using easyvet software to identify cases eligible for inclusion in the
Anika Mische, Kerstin Müller
wiley   +1 more source