BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB.
Hallbauer, UM +4 more
core +1 more source
Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]
Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba +9 more
core +3 more sources
Drug-Resistant Tuberculosis--Current Dilemmas, Unanswered Questions, Challenges and Priority Needs [PDF]
Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short course (DOTS), a cost-effective strategy to contain the tuberculosis ...
Abubakar, Ibrahim +23 more
core +1 more source
Antibiotic resistance genes in helicobacter pylori isolates from gastric biopsies of patients with gastrointestinal diseases in Golestan province, Iran [PDF]
Background: Antibiotic resistance in Helicobacter pylori infections can lead to treatment failure. This study aims to evaluate the antibiotic resistance to metronidazole, clarithromycin, and fluoroquinolone in H.
Azam Shareh +5 more
doaj
Rapid prediction of inducible clarithromycin resistance in Mycobacterium abscessus
We have developed a single tube TaqMan(®) real-time PCR assay that differentiates the full-length and truncated erm(41) gene to predict inducible resistance to clarithromycin in Mycobacterium abscessus. A study of 87 clinical isolates found this assay to be 90.8% concordant to conventional drug susceptibility testing results for the prediction of ...
Yan Chun, Zhu +4 more
openaire +2 more sources
ABSTRACT Background High antibiotic resistance and limited tetracycline accessibility severely restrict the clinical application of classic bismuth quadruple therapy (BQT), creating an urgent demand for alternative regimens. Methods A systematic search was conducted in PubMed, Embase, Cochrane Library, and Web of Science up to June 3, 2025, for trials ...
Qi‐Qi Guo +7 more
wiley +1 more source
\u3cem\u3eHelicobacter pylori\u3c/em\u3e infection in Havana, Cuba. Prevalence and \u3cem\u3ecagA\u3c/em\u3e status of the strains [PDF]
There is a great paucity of information about Helicobacter pylori infection in the countries of the Caribbean basin. Almost no studies have been performed to determine the prevalence, antibiotic resistance or virulence factors of the bacterium.
Camou-Juncas, Christine +12 more
core +1 more source
New and Improved Diagnostics for Detection of Drug-Resistant Pulmonary Tuberculosis. [PDF]
PURPOSE OF REVIEW: Tuberculosis (TB) remains a global emergency and continues to kill 1.7 million people globally each year. Drug-resistant TB is now well established throughout the world and most TB patients are not being screened for drug resistance ...
Affolabi +41 more
core +1 more source
Rationalizing Proton Pump Inhibitor Use: Southeast Asia Consensus Recommendations
ABSTRACT Background and Aim Proton pump inhibitors (PPIs) are integral to managing many gastrointestinal conditions. However, the prevalent inappropriate PPI prescription across Southeast Asia (SEA) is concerning. Given the absence of locally tailored recommendations to inform clinical practice, this consensus document aims to provide recommendations ...
Somchai Leelakusolvong +13 more
wiley +1 more source
Antimicrobial Resistance: We Must Pursue a Collaborative, Global Approach and Use a "One Health" Approach. [PDF]
Treating infection is a key part of the work of most clinicians [...]
Lipman, J, Lonsdale, DO
core +1 more source

