Results 31 to 40 of about 18,197 (177)

Helicobacter pylori Primary and Secondary Genotypic Resistance to Clarithromycin and Levofloxacin Detection in Stools: A 4-Year Scenario in Southern Italy

Antibiotics, 2020
Antibiotic resistance has become an emerging problem for treating Helicobacter pylori (H. pylori) infection. Clarithromycin and levofloxacin are two key antibiotics used for its eradication. Therefore, we reviewed our experience with genotypic resistance
Giuseppe Losurdo, Floriana Giorgio, Maria Pricci, Bruna Girardi, Francesco Russo, Giuseppe Riezzo, Manuela Martulli, Mariano Piazzolla, Francesco Cocomazzi, Francesco Abbruzzi, Elisabetta Parente, Rosa Paolillo, Alessia Mileti, Andrea Iannone, Mariabeatrice Principi, Enzo Ierardi, Alfredo Di Leo   +16 more
doaj   +1 more source

Rapid screening of clarithromycin resistance in Helicobacter pylori by pyrosequencing [PDF]

Journal of Medical Microbiology, 2007
Helicobacter pylori infections can be effectively treated with clarithromycin, a macrolide, in combination with other antibiotics, such as amoxicillin, tetracycline or metronidazole. The failure of H. pylori eradication is mainly associated with macrolide-resistant strains.
Karen-Anja, Moder, Franziska, Layer, Wolfgang, König, Brigitte, König   +3 more
openaire   +2 more sources

Lack of association between rrl and erm(41) mutations and clarithromycin resistance in Mycobacterium abscessus complex

Memorias do Instituto Oswaldo Cruz
BACKGROUND Mycobacterium abscessus complex (MABC) includes species with high resistance rates among mycobacterial pathogens. In fact, MABC infections may not respond to clarithromycin treatment, which has historically been very effective against MABC ...
Maiara dos Santos Carneiro, Luciana de Souza Nunes, Simone Maria Martini de David, Afonso Luis Barth   +3 more
doaj   +1 more source

Safety and tolerability of clarithromycin in the treatment of multidrug-resistant tuberculosis [PDF]

European Respiratory Journal, 2017
Clarithromycin had a good tolerability and safety profile as assessed in MDR-TB patients receiving prolonged treatment http://ow.ly ...
Anne-Fleur Louise Van der Paardt, Onno W. Akkerman, Gina Gualano, Fabrizio Palmieri, Lina Davies Forsman, Alena Aleksa, Simon Tiberi, Wiel C.M. de Lange, Mathieu S. Bolhuis, Alena Skrahina, Dick van Soolingen, Jos G.W. Kosterink, Giovanni Battista Migliori, Tjip S. van der Werf, Jan-Willem C. Alffenaar   +14 more
openaire   +3 more sources

Clarithromycin overcomes resistance to lenalidomide and dexamethasone in multiple myeloma [PDF]

American Journal of Hematology, 2014
The combination of clarithromycin, lenalidomide and dexamethasone (BiRd) has led to highly durable responses in newly diagnosed myeloma. However, the ability of clarithromycin to overcome resistance to lenalidomide and dexamethasone (Rd) is not known.
Nilanjan, Ghosh, Noah, Tucker, Marianna, Zahurak, Jocelyn, Wozney, Ivan, Borrello, Carol Ann, Huff   +5 more
openaire   +2 more sources

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

The Contribution of Efflux Pumps in Mycobacterium abscessus Complex Resistance to Clarithromycin

Antibiotics, 2019
The basis of drug resistance in Mycobacterium abscessus is still poorly understood. Nevertheless, as seen in other microorganisms, the efflux of antimicrobials may also play a role in M. abscessus drug resistance. Here, we investigated the role of efflux
Júlia S. Vianna, Diana Machado, Ivy B. Ramis, Fábia P. Silva, Dienefer V. Bierhals, Michael Andrés Abril, Andrea von Groll, Daniela F. Ramos, Maria Cristina S. Lourenço, Miguel Viveiros, Pedro E. Almeida da Silva   +10 more
doaj   +1 more source

Systemic Corticosteroids in the Management of Sinonasal Disease: An Evidence‐Based Expert Review

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prevalent, heterogeneous inflammatory disease associated with significant morbidity. Systemic corticosteroids (SCS) are commonly prescribed for their anti‐inflammatory effects, but cumulative exposure carries risks, including metabolic, cardiovascular, and skeletal complications.
Andrew Thamboo, Deanna Gigliotti, Eugenio De Corso, Stella Lee, Benjamin S. Bleier, Christopher J. Chin, Marie‐Noelle Corriveau, Valerie Hox, Claire Hopkins, Peter H. Hwang, Arif Janjua, Ludger Klimek, Daniel Lee, John Lee, Amber Luong, Geoffrey Mortuaire, Joaquim Mullol, Zara M. Patel, John Scott, Doron Sommer, Leigh Sowerby, Marc Tewfik, Beatrice Voizard, Martin Wagenmannm, Sarah K. Wise, Jonathan Yip, Quirina Thompson, Martin Desrosiers, Yvonne Chan   +28 more
wiley   +1 more source

High Levels of Helicobacter pylori Antimicrobial Resistance in Ireland—A Multicentre Study

Microorganisms
Resistance surveillance programmes are essential for choosing the most appropriate eradication therapy for the stomach pathogen Helicobacter pylori. This study aimed to determine H. pylori antimicrobial resistance rates in Ireland. H. pylori was cultured
Thomas J. Butler, Stephen Molloy, Atiyekeogbebe Douglas, Denise Brennan, Rebecca FitzGerald, Conor Costigan, Vikrant Parihar, Kevin Van Der Merwe, Serhiy Semenov, Donal Tighe, Sharon Hough, David Kevans, Colm O’Morain, Deirdre McNamara, Sinéad Marian Smith   +14 more
doaj   +1 more source

Evaluation of multiplex ARMS-PCR for detection of Helicobacter pylori mutations conferring resistance to clarithromycin and levofloxacin

Gut Pathogens, 2020
Background Helicobacter pylori bacterium is a major cause of gastritis. With increasing use of antibiotics to treat infections, mutation resistant strains have emerged in most human populations.
Yangxia Li, Tangshan Lv, Chaochao He, Hongyan Wang, David S. Cram, Linfu Zhou, Jun Zhang, Weiqin Jiang   +7 more
doaj   +1 more source