Results 31 to 40 of about 18,807 (182)

A Novel Reduction Strategy of Clarithromycin Resistance in Helicobacter pylori [PDF]

Jundishapur Journal of Microbiology, 2014
Antibiotic resistance is a major therapeutic problem in patients infected with Helicobacter pylori. H. pylori clarithromycin resistant mutants have been evolved during antibiotic therapy, this is mainly due to 23s rRNA point mutations.In the present study, we investigated anti-mutational features of four traditionally Iranian medicinal plants on three ...
Tadjrobehkar, Omid, Abdollahi, Hamid
openaire   +2 more sources

Clarithromycin overcomes resistance to lenalidomide and dexamethasone in multiple myeloma [PDF]

American Journal of Hematology, 2014
The combination of clarithromycin, lenalidomide and dexamethasone (BiRd) has led to highly durable responses in newly diagnosed myeloma. However, the ability of clarithromycin to overcome resistance to lenalidomide and dexamethasone (Rd) is not known.
Nilanjan, Ghosh, Noah, Tucker, Marianna, Zahurak, Jocelyn, Wozney, Ivan, Borrello, Carol Ann, Huff   +5 more
openaire   +2 more sources

Lack of association between rrl and erm(41) mutations and clarithromycin resistance in Mycobacterium abscessus complex

Memorias do Instituto Oswaldo Cruz
BACKGROUND Mycobacterium abscessus complex (MABC) includes species with high resistance rates among mycobacterial pathogens. In fact, MABC infections may not respond to clarithromycin treatment, which has historically been very effective against MABC ...
Maiara dos Santos Carneiro, Luciana de Souza Nunes, Simone Maria Martini de David, Afonso Luis Barth   +3 more
doaj   +1 more source

CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension

British Journal of Clinical Pharmacology, EarlyView.
Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien, Burabha Pussadhamma, Sirimas Kanjanawart, Thikhumporn Areesinpitak, Nontaya Nakkam, Chingching Foocharoen, Wichittra Tassaneeyakul, Suda Vannaprasaht   +7 more
wiley   +1 more source

Safety and tolerability of clarithromycin in the treatment of multidrug-resistant tuberculosis [PDF]

European Respiratory Journal, 2017
Clarithromycin had a good tolerability and safety profile as assessed in MDR-TB patients receiving prolonged treatment http://ow.ly ...
Anne-Fleur Louise Van der Paardt, Onno W. Akkerman, Gina Gualano, Fabrizio Palmieri, Lina Davies Forsman, Alena Aleksa, Simon Tiberi, Wiel C.M. de Lange, Mathieu S. Bolhuis, Alena Skrahina, Dick van Soolingen, Jos G.W. Kosterink, Giovanni Battista Migliori, Tjip S. van der Werf, Jan-Willem C. Alffenaar   +14 more
openaire   +3 more sources

Management of Antibiotic-Resistant Helicobacter pylori Infection: Perspectives from Vietnam

Gut and Liver, 2019
Antibiotic resistance is the most important factor leading to the failure of eradication regimens. This review focuses on the prevalence of Helicobacter pylori primary and secondary resistance to clarithromycin, metronidazole, amoxicillin, levofloxacin ...
Vu Van Khien, Duong Minh Thang, Tran Manh Hai, Nguyen Quang Duat, Pham Hong Khanh, Dang Thuy Ha, Tran Thanh Binh, Ho Dang Quy Dung, Tran Thi Huyen Trang, Yoshio Yamaoka   +9 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Rapid screening of clarithromycin resistance in Helicobacter pylori by pyrosequencing [PDF]

Journal of Medical Microbiology, 2007
Helicobacter pylori infections can be effectively treated with clarithromycin, a macrolide, in combination with other antibiotics, such as amoxicillin, tetracycline or metronidazole. The failure of H. pylori eradication is mainly associated with macrolide-resistant strains.
Karen-Anja, Moder, Franziska, Layer, Wolfgang, König, Brigitte, König   +3 more
openaire   +2 more sources

Helicobacter pylori Resistance to Clarithromycin in the Russian Federation [PDF]

Effective Pharmacotherapy, 2020
Purpose – the systematization of data on the resistance of Helicobacter pylori to clarithromycin in the Russian Federation. Material and methods. Necessary investigations were searched in the electronic databases MEDLINE/PubMed, EMBASE, Cochrane, and the Russian Science Citation Index (RSCI), published between January and September, 2020.
I.V. Mayev, D.N. Andreyev, D.S. Bordin, Yu.A. Kucheryavy, L.V. Kudryavtseva, Ye.S. Vyuchnova, Ye.G. Lebedeva, D.T. Dicheva, A.K. Fomenko   +8 more
openaire   +1 more source