Results 41 to 50 of about 57,560 (274)

Blood Concentration of Cabazitaxel in a Patient Whose General Condition Worsened with Concomitant Use of Clarithromycin

open access: yesCase Reports in Oncology, 2023
We encountered a case in which the general condition of a patient receiving cabazitaxel worsened with concomitant use of clarithromycin. Cabazitaxel is metabolized mainly by CYP3A4, and the frequency of adverse events is known to increase with increasing
Shigeaki Katsumi   +5 more
doaj   +1 more source

GenoType NTM-DR Performance Evaluation for Identification of Mycobacterium avium Complex and Mycobacterium abscessus and Determination of Clarithromycin and Amikacin Resistance

open access: yesJournal of Clinical Microbiology, 2019
We evaluated the GenoType NTM-DR (NTM-DR) line probe assay for identifying Mycobacterium avium complex (MAC) species and Mycobacterium abscessus subspecies and for determining clarithromycin and amikacin resistance. Thirty-eight reference strains and 145
H. Huh   +12 more
semanticscholar   +1 more source

Polymorphism of virulence genes and biofilm associated with in vitro induced resistance to clarithromycin in Helicobacter pylori

open access: yesGut Pathogens, 2023
Background Clarithromycin-containing triple therapy is commonly used to treat Helicobacter pylori infections. Clarithromycin resistance is the leading cause of H. pylori treatment failure. Understanding the specific mutations that occur in H.
Naim Asyraf Rosli   +5 more
doaj   +1 more source

Poly(lactic acid)/clarithromycin with metals dioxides nanoparticles: Preparation and performance under ultraviolet irradiation

open access: yesMaterials Science for Energy Technologies
Different polylactic acid (PLA) thin films containing clarithromycin and a number of metal oxide nanoparticles (magnesium, titanium, zinc, and nickel) dioxides were created. Low dosages of metal oxides (0.01% by weight) and clarithromycin (0.5% by weight)
Hadeel Adil   +8 more
doaj   +1 more source

Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population [PDF]

open access: yes
Background: In Iran, there is insufficient information on the efficacy of Helicobacter pylori eradication regimens shorter than 10 days. This study aims at assessing the efficacy of 4- and 7-day H. pylori eradication regimens in a high-incidence area of
میکاییلی, جواد   +15 more
core   +1 more source

PLGA nanocapsules improve the delivery of clarithromycin to kill intracellular Staphylococcus aureus and Mycobacterium abscessus.

open access: yesNanomedicine : nanotechnology, biology, and medicine, 2019
Drug delivery systems are promising for targeting antibiotics directly to infected tissues. To reach intracellular Staphylococcus aureus and Mycobacterium abscessus, we encapsulated clarithromycin in PLGA nanocapsules, suitable for aerosol delivery by ...
F. Dimer   +12 more
semanticscholar   +1 more source

Detection of A2142C, A2142G, and A2143G Mutations in 23s rRNA Gene Conferring Resistance to Clarithromycin among Helicobacter pylori Isolates in Kerman, Iran [PDF]

open access: yesIranian Journal of Medical Sciences, 2011
Background: Clarithromycin resistance in Helicbacter pylori has been found to be associated with point mutations in 23s rRNA gene leads to reduced affinity of the antibiotic to its ribosomal target or changing the site of methylation.
Hamid Abdollahi   +4 more
doaj  

Primary resistance to clarithromycin, metronidazole and amoxicillin of Helicobacter pylori isolated from Tunisian patients with peptic ulcers and gastritis: a prospective multicentre study

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2010
Background The frequency of primary resistance to antibiotics in H. pylori isolates is increasing worldwide. In Tunisia, there are limited data regarding the pattern of H. pylori antibiotic primary resistance. Aim To evaluate the primary resistance of H.
Ben Mansour Khansa   +21 more
doaj   +1 more source

The Contribution of Efflux Pumps in Mycobacterium abscessus Complex Resistance to Clarithromycin

open access: yesAntibiotics, 2019
The basis of drug resistance in Mycobacterium abscessus is still poorly understood. Nevertheless, as seen in other microorganisms, the efflux of antimicrobials may also play a role in M. abscessus drug resistance. Here, we investigated the role of efflux
J. Vianna   +10 more
semanticscholar   +1 more source

Lack of association between rrl and erm(41) mutations and clarithromycin resistance in Mycobacterium abscessus complex

open access: yesMemorias do Instituto Oswaldo Cruz
BACKGROUND Mycobacterium abscessus complex (MABC) includes species with high resistance rates among mycobacterial pathogens. In fact, MABC infections may not respond to clarithromycin treatment, which has historically been very effective against MABC ...
Maiara dos Santos Carneiro   +3 more
doaj   +1 more source

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