Results 41 to 50 of about 41,122 (231)

Lipopolysaccharide glycotyping of clarithromycin-resistant and clarithromycin-susceptible Canadian isolates of Helicobacter pylori

open access: yes, 2014
Lipopolysaccharide (LPS) of Helicobacter pylori exhibits several unique structures, such as Lewis (Le) antigens, \u3b1-1, 6-glucan, and DD-heptan.
Altman, E.   +3 more
core   +1 more source

In vivo Evaluation of Amoxicillin Trihydrate and Clarithromycin-Loaded Mucoadhesive Microspheres for H. pylori Eradication [PDF]

open access: yes, 2013
Purpose: To evaluate in vivo H. pylori clearance efficacy of formulated mucoadhesive microspheres of amoxicillin trihydrate and clarithromycin. Methods: Amoxicillin trihydrate and clarithromycin mucoadhesive microspheres were prepared by solvent ...
Ramanathan, S, Nallasamy, V, Perumal, P
core   +3 more sources

Lack of association between rrl and erm(41) mutations and clarithromycin resistance in Mycobacterium abscessus complex

open access: yesMemorias do Instituto Oswaldo Cruz
BACKGROUND Mycobacterium abscessus complex (MABC) includes species with high resistance rates among mycobacterial pathogens. In fact, MABC infections may not respond to clarithromycin treatment, which has historically been very effective against MABC ...
Maiara dos Santos Carneiro   +3 more
doaj   +1 more source

Detection of A2142C, A2142G, and A2143G Mutations in 23s rRNA Gene Conferring Resistance to Clarithromycin among Helicobacter pylori Isolates in Kerman, Iran [PDF]

open access: yesIranian Journal of Medical Sciences, 2011
Background: Clarithromycin resistance in Helicbacter pylori has been found to be associated with point mutations in 23s rRNA gene leads to reduced affinity of the antibiotic to its ribosomal target or changing the site of methylation.
Hamid Abdollahi   +4 more
doaj  

Polymorphism of virulence genes and biofilm associated with in vitro induced resistance to clarithromycin in Helicobacter pylori

open access: yesGut Pathogens, 2023
Background Clarithromycin-containing triple therapy is commonly used to treat Helicobacter pylori infections. Clarithromycin resistance is the leading cause of H. pylori treatment failure. Understanding the specific mutations that occur in H.
Naim Asyraf Rosli   +5 more
doaj   +1 more source

Update on clarithromycin resistance in Helicobacter pylori in Hong Kong and its effect on clarithromycin-based triple therapy

open access: yes, 2006
Aim: To determine the antibiotic susceptibility of Helicobacter pylori and evaluate the efficacy of a clarithromycin-based triple therapy in relation to antibiotic resistance.
Xia, HHX   +11 more
core   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed   +7 more
wiley   +1 more source

The role of clarithromycin in the management of chronic rhinosinusitis

open access: yes, 2021
The anti-inflammatory effects of macrolides, particularly clarithromycin, have been described in patients with chronic rhinosinusitis without polyps and also other chronic inflammatory airway diseases.
Canevari FR.   +5 more
core   +2 more sources

Genotypic and Phenotypic Resistance to Clarithromycin in Helicobacter pylori Strains

open access: yes, 2020
Background: The increasing prevalence of antimicrobial resistance, together with the lack of novel treatment options, negatively affects successful eradication of Helicobacter pylori.
Ji Yong Ahn   +25 more
core   +1 more source

CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien   +7 more
wiley   +1 more source

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