Results 61 to 70 of about 57,560 (274)

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Clarithromycin in early pregnancy and the risk of miscarriage and malformation: a register based nationwide cohort study. [PDF]

PLoS ONE, 2013
BACKGROUND: The antibiotic clarithromycin has been associated with fetal loss in animals and a study has found a doubling in the frequency of miscarriages among women using clarithromycin in pregnancy.
Jon Trærup Andersen, Morten Petersen, Espen Jimenez-Solem, Espen Jimenez-Solem, Kasper Broedbaek, Nadia Lyhne Andersen, Christian Torp-Pedersen, Niels Keiding, Henrik Enghusen Poulsen   +8 more
doaj   +1 more source

Lipopolysaccharide glycotyping of clarithromycin-resistant and clarithromycin-susceptible Canadian isolates of Helicobacter pylori

, 2014
Lipopolysaccharide (LPS) of Helicobacter pylori exhibits several unique structures, such as Lewis (Le) antigens, \u3b1-1, 6-glucan, and DD-heptan.
Altman, E., Harrison, B.A., Chandan, V., Slinger, R.   +3 more
core   +1 more source

Influence of clarithromycin on the bactericidal effect of amoxicillin in patients infected with clarithromycin-resistant strains of H. pylori [PDF]

, 2020
Suzuki et al. reported that the VA-Dual therapy was better at eradicating the clarithromycin-resistant strains of H. pylori than the VAC-Triple therapy.
Higuchi, Tomohiro, Sugimoto, Ken, Furuta, Takahisa, Tani, Shinya, Iwaizumi, Moriya, Kagami, Takuma, Hamaya, Yasushi, Miyajima, Hiroaki, Umemura, Kazuo, Osawa, Satoshi, Yamade, Mihoko, Suzuki, Takahiro   +11 more
core   +1 more source

Clarithromycin Enhances the Antibacterial Activity and Wound Healing Capacity in Type 2 Diabetes Mellitus by Increasing LL-37 Load on Neutrophil Extracellular Traps

Frontiers in Immunology, 2018
Background: Type 2 diabetes mellitus (T2D) is characterized by susceptibility to bacterial infections and impaired wound healing. Neutrophil extracellular traps (NETs) and the cathelicidin antimicrobial peptide LL-37 have been implicated both in defense ...
Athanasios Arampatzioglou, Dimitrios Papazoglou, T. Konstantinidis, A. Chrysanthopoulou, Alexandros Mitsios, Iliana Angelidou, I. Maroulakou, K. Ritis, P. Skendros   +8 more
semanticscholar   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Clarithromycin resistance and female gender affect Helicobacter pylori eradication failure in chronic gastritis

The Korean Journal of Internal Medicine, 2018
Background/Aims The eradication rate of the first-line triple therapy (a proton pump inhibitor, clarithromycin, and amoxicillin) for Helicobacter pylori infection has gradually decreased in Korea.
Y. Chang, W. Ko, C. Oh, Y. Park, S. Oh, J. Moon, Jun-Hyung Cho, Jung-Wook Kim, J. Jang   +8 more
semanticscholar   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Mutations in the 23S rRNA gene are associated with clarithromycin resistance in Helicobacter pylori isolates in Brazil

Annals of Clinical Microbiology and Antimicrobials, 2003
Background Resistance of Helicobacter pylori to clarithromycin has been associated with A2142G and A2143G point mutations in the 23S rRNA gene. Thus, the purpose of the present study was to determine the prevalence of each mutation in 52 clarithromycin ...
Godoy Anita PO, Benvengo Yune HB, Miranda Maira CB, Vitiello Lea, Ribeiro Marcelo L, Mendonca Sergio, Pedrazzoli José   +6 more
doaj   +1 more source

Bismuth-Based Quadruple Therapy versus Metronidazole-Intensified Triple Therapy as a First-Line Treatment for Clarithromycin-Resistant Helicobacter pylori Infection: A Multicenter Randomized Controlled Trial

Gut and Liver, 2022
Background/Aims: Clarithromycin resistance is a main factor for treatment failure in the context of Helicobacter pylori infection. However, the treatment regimen for clarithromycin-resistant H. pylori infection has not yet been determined.
Seung In Seo, Hyun Lim, Chang Seok Bang, Young Joo Yang, Gwang Ho Baik, Sang Pyo Lee, Hyun Joo Jang, Sea Hyub Kae, Jinseob Kim, Hak Yang Kim, Woon Geon Shin   +10 more
doaj   +1 more source