Results 21 to 30 of about 40,048 (221)

Efficacy of clarithromycin against experimentally induced pneumonia caused by clarithromycin-resistant Haemophilus influenzae in mice. [PDF]

open access: yes, 2010
Clarithromycin is a 14-member lactone ring macrolide with potent activity against Haemophilus influenzae, including ampicillin-resistant strains. We evaluated the in vivo efficacy of clarithromycin at 40 mg/day and 100 mg/day for 3 days in the treatment ...
Araki, Nobuko   +10 more
core   +1 more source

Effect of Clarithromycin on Enhancement of Doxorubicin-induced Cytotoxicity and Apoptosis in A549 Tumor-Cell Line

open access: yesJournal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Nowadays, multi-drug regimens or combination therapy are new approaches in cancer treatment that combine two or several therapeutic agents.
Mohammad Shokrzadeh   +2 more
doaj  

Therapeutic efficacy of macrolides in management of patients with mild COVID-19

open access: yesScientific Reports, 2021
Evidence on the efficacy of adding macrolides (azithromycin or clarithromycin) to the treatment regimen for COVID-19 is limited. We testify whether adding azithromycin or clarithromycin to a standard of care regimen was superior to standard of supportive
Alaa Rashad   +9 more
doaj   +1 more source

Clarithromycin resistance and 23S rRNA gene point mutations of Helicobacter pylori infection in children

open access: yesThe Turkish Journal of Pediatrics, 2016
This study aims to evaluate Helicobacter pylori with clarithromycin resistant genotypes in Manisa region, Turkey. Two hundred patients, who received diagnosis of Helicobacter pylori infection histopathologically, were included.
Yeliz Çağan-Appak   +5 more
doaj   +1 more source

A randomized placebo-controlled phase II study of clarithromycin or placebo combined with VCD induction therapy prior to high-dose melphalan with stem cell support in patients with newly diagnosed multiple myeloma

open access: yesExperimental Hematology & Oncology, 2018
Background The objective of this randomized placebo-controlled study was to investigate the efficacy and safety of clarithromycin in combination with bortezomib–cyclophosphamide–dexamethasone (VCD) in patients with newly diagnosed multiple myeloma ...
Henrik Gregersen   +9 more
doaj   +1 more source

Clarithromycin attenuates IL-13–induced periostin production in human lung fibroblasts

open access: yesRespiratory Research, 2017
Background Periostin is a biomarker indicating the presence of type 2 inflammation and submucosal fibrosis; serum periostin levels have been associated with asthma severity.
Kosaku Komiya   +12 more
doaj   +1 more source

Poly(lactic acid)/clarithromycin with metals dioxides nanoparticles: Preparation and performance under ultraviolet irradiation

open access: yesMaterials Science for Energy Technologies
Different polylactic acid (PLA) thin films containing clarithromycin and a number of metal oxide nanoparticles (magnesium, titanium, zinc, and nickel) dioxides were created. Low dosages of metal oxides (0.01% by weight) and clarithromycin (0.5% by weight)
Hadeel Adil   +8 more
doaj   +1 more source

Blood Concentration of Cabazitaxel in a Patient Whose General Condition Worsened with Concomitant Use of Clarithromycin

open access: yesCase Reports in Oncology, 2023
We encountered a case in which the general condition of a patient receiving cabazitaxel worsened with concomitant use of clarithromycin. Cabazitaxel is metabolized mainly by CYP3A4, and the frequency of adverse events is known to increase with increasing
Shigeaki Katsumi   +5 more
doaj   +1 more source

Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population [PDF]

open access: yes
Background: In Iran, there is insufficient information on the efficacy of Helicobacter pylori eradication regimens shorter than 10 days. This study aims at assessing the efficacy of 4- and 7-day H. pylori eradication regimens in a high-incidence area of
میکاییلی, جواد   +15 more
core   +1 more source

Is Only Clarithromycin Susceptibility Important for the Successful Eradication of Helicobacter pylori?

open access: yesAntibiotics, 2020
Resistance to clarithromycin and other antibiotics included in the eradication regimen, such as amoxicillin and metronidazole, is important for Helicobacter pylori (H. pylori) eradication.
Young Min Kim   +6 more
doaj   +1 more source

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