Formation of CO<sub>2</sub>-dependent small-colony variants (SCVs) in methicillin-resistant <i>Staphylococcus aureus</i> mediated by a single point mutation in <i>mpsB</i>. [PDF]
Chen S +9 more
europepmc +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Single Point Mutation Abolishes Water Capture in Germacradien-4-ol Synthase. [PDF]
González Requena V +3 more
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Different Infection Structures and Point Mutation of Diaporthe citri Showing Resistant against Systemic Fungicides. [PDF]
Soe ZZ, Shin YH, Jeun YC.
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
RID is required for both repeat-induced point mutation and nucleation of a novel transitional heterochromatic state for euchromatic repeats. [PDF]
He Z +11 more
europepmc +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
A point mutation in the <i>IAA14</i> promoter enhances callus formation and regeneration. [PDF]
Cao H, Zhang X, Li F, Han Z, Ding B.
europepmc +1 more source

