Results 211 to 220 of about 7,351,528 (349)

Single Point Mutation in Bin/Amphiphysin/Rvs (BAR) Sequence of Endophilin Impairs Dimerization, Membrane Shaping, and Src Homology 3 Domain-mediated Partnership [PDF]

, 2011
Anna Gortat, Mabel Jouve, Christian Vannier, Anne Schmidt   +3 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Resistance Assessment for Oxathiapiprolin in Phytophthora capsici and the Detection of a Point Mutation (G769W) in PcORP1 that Confers Resistance [PDF]

, 2016
Jianqiang Miao, Meng Cai, Xue Dong, Li Liu, Dong Lin, Can Zhang, Zhili Pang, Xili Liu   +7 more
openalex   +1 more source

DeNovoGear: de novo indel and point mutation discovery and phasing

Nature Methods, 2013
Avinash Ramu, M. J. Noordam, R. Schwartz, A. Wuster, M. Hurles, R. Cartwright, D. Conrad   +6 more
semanticscholar   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

A single point mutation on FLT3L-Fc protein increases the risk of immunogenicity. [PDF]

Front Immunol
Qin D, Phung Q, Wu P, Yin Z, Tam S, Tran P, ElSohly AM, Gober J, Hu Z, Zhou Z, Cohen S, He D, Bainbridge TW, Kemball CC, Zarzar J, Sreedhara A, Stephens N, Decalf J, Moussion C, Ye Z, Balazs M, Li Y.   +21 more
europepmc   +1 more source

Structural effects of point mutations in proteins

, 2018
Suvethigaa Shanthirabalan, Jacques Chomilier, Mathilde Carpentier   +2 more
openalex   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Assessing data size requirements for training generalizable sequence-based TCR specificity models via pan-allelic MHC-I point-mutation ligandome evaluation. [PDF]

Sci Rep
Delaunay A, McGibbon M, Djermani B, Gorbushin N, Chaves García-Mascaraque S, Rayment I, Kizhvatov I, Petit C, Lang M, Beguir K, Sahin U, Copoiu L, Lopez Carranza N, Tovchigrechko A.   +13 more
europepmc   +1 more source

A spontaneous point mutation in the single 23S rRNA gene of the thermophilic arachaeon Sulfolobus acidocaldarius confers multiple drug resistance [PDF]

, 1994
Claus Aagaard, Hang Phan, Siro Trevisanato, R.A. Garrett   +3 more
openalex   +1 more source