Results 241 to 250 of about 6,585,062 (339)

A Single Interfacial Point Mutation Rescues Solution Structure Determination of the Complex of HMG-D with a DNA Bulge. [PDF]

Chembiochem
Hill GR, Yang JC, Easton LE, Cerdan R, McLaughlin SH, Stott K, Travers AA, Neuhaus D.   +7 more
europepmc   +1 more source

Point mutations in the uroporphyrinogen III synthase gene in congenital erythropoietic porphyria (Gunther's disease) [PDF]

, 1990
JC Deybach, Hubert de Verneuil, Samia Boulechfar, Bernard Grandchamp, Y Nordmann   +4 more
openalex   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

The point mutation A1387G in the 16S rRNA gene confers aminoglycoside resistance in Campylobacter jejuni and Campylobacter coli. [PDF]

Antimicrob Agents Chemother
Zarske M, Werckenthin C, Golz JC, Stingl K.   +3 more
europepmc   +1 more source

Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages. [PDF]

Proc Natl Acad Sci U S A
Szyszka TN, Andreas MP, Lie F, Miller LM, Adamson LSR, Fatehi F, Twarock R, Draper BE, Jarrold MF, Giessen TW, Lau YH.   +10 more
europepmc   +2 more sources

Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli

FEBS Open Bio, EarlyView.
BacA, PgpB, and YbjG phosphatases are involved in undecaprenyl phosphate (C55P) synthesis in Escherichia coli. We analyzed the lipid contents and the gene expression in the gene‐disruption strains. Undecaprenyl diphosphate (C55PP) level increased in the bacA, ybjG double‐disruption strain, but C55P levels were similar in all strains.
Tomotaka Jitsukawa, Yasushi Shigeri, Shingo Fujisaki   +2 more
wiley   +1 more source

Evaluation of bla_OXA-48-like point mutation carbapenemase-producing Enterobacterales in Prapokklao Hospital, Thailand. [PDF]

Microbiol Spectr
Santajit S, Tunyong W, Kong-Ngoen T, Arsheewa W, Hinthong W, Pumirat P, Sookrung N, Indrawattana N.   +7 more
europepmc   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection. [PDF]

Zool Res
Liu Y, Yang L, Xiang HY, Niu M, Deng JC, Li XY, Hao WJ, Ou-Yang HS, Liu TY, Tang XC, Pang DX, Yuan HM.   +11 more
europepmc   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

FEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian, Di Liu, Bing Liu, Yu Lan, Jie Zhou   +4 more
wiley   +1 more source