Results 111 to 120 of about 2,456,337 (301)

Improving the Physical Exam with Technology - Point of Care Ultrasound [PDF]

, 2017
Point of Care Ultrasound is rapidly becoming standard of care for utilization in real time medical diagnostics and decision making. As such we sought to introduce ultrasound to medical students beginning in their first year and specifically incorporating
Pedram, Sammy
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Point-of-care testing [PDF]

, 2019
Introducción: la evaluación ultrasonográfica del tracto reproductivo en las yeguas es uno de los procedimientos más confiables en la actualidad para el diagnóstico y monitoreo de la preñez. Esta herramienta tiene la capacidad de predecir el impacto potencial que algunas enfermedades generan en la calidad y salud reproductiva de las yeguas.
openaire   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

The conduct of quality control and quality assurance testing for PoCT outside the laboratory [PDF]

, 2010
Within pathology laboratories, quality assessment, internal quality control (QC) and external quality assurance (EQA) are integral components of a laboratory’s quality system.
Gill, Janice P, Shephard, Mark Douglas
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Point-of-care testing in diabetes management

Romanian Journal of Laboratory Medicine, 2019
The prevalence of diabetes mellitus (DM) has rapidly increased over the last decades, reaching epidemic magnitudes, particularly in lowand middle-income countries. Point-of-care (POC) technology enables decision making near or at the site of patient care.
Cozma Angela, Vonica Camelia, Sitar-Taut Adela, Fodor Adriana   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Economic evaluation of point-of-care testing in the remote primary health care setting of Australia’s Northern Territory

ClinicoEconomics and Outcomes Research, 2018
Brooke A Spaeth,1 Billingsley Kaambwa,2 Mark DS Shephard,1 Rodney Omond3 1Flinders University International Centre for Point-of-Care Testing, Flinders University, Adelaide, SA, Australia; 2Health Economics Unit, College of Medicine and Public Health ...
Spaeth BA, Kaambwa B, Shephard MDS, Omond R   +3 more
doaj  

Improving Resulted Hemoglobin A1c Rates: A Feasibility Study for Point-of-Care Hemoglobin A1c Testing at an Urban Family Medicine Office [PDF]

, 2017
Study Aims: Our practice’s goal is to increase the number of up to date hemoglobin A1c for diabetic patients seen at JFMA in order to help improve glycemic control The aim of this study is to see if point of care (POC) hemoglobin A1C is a feasible ...
Altshuler, MD, Marc, Amadi, MD, Grace, Aragon, MD, Miranda, Askie, MD, MPH, Phoebe, Bardet, MD, Kyle, Chung, MD, Daniel, Kuperman, MD, MPH, Mariana R., Lai, MD, Sunny, Parente, MD, Laura, Parra, MD, Yury, Reaves, MD, Bruce, Woods, MD, Anna   +11 more
core   +1 more source