Results 91 to 100 of about 811,999 (309)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Investigation of the Agreement between Glucose Meters Used for Glucose Measurement and Central Laboratory Measurements

Ahi Evran Medical Journal
Purpose: Blood glucose measurement is of great importance in preventing complications and reducing mortality and morbidity for several diseases. Glucometers are used by any healthcare professionals.
Esra Yılmaz , Medeni Arpa, Bayram Şen, Mehmet Çingirt   +3 more
doaj   +1 more source

Quantum Dot-Based Lateral Flow Immunoassay as Point-of-Care Testing for Infectious Diseases: A Narrative Review of Its Principle and Performance

, 2022
Infectious diseases are the world’s greatest killers, accounting for millions of deaths worldwide annually, especially in low-income countries. As the risk of emerging infectious diseases is increasing, it is critical to rapidly diagnose infections
Ismail Aziah, Ahmad Najib, Mohamad, Mehmet Ozsoz, Ozsoz, Mehmet, Khalid, Muhammad Fazli, Kasturi Selvam, Aziah, Ismail, Mohamad Ahmad Najib, Selvam, Kasturi, Muhammad Fazli Khalid   +9 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Where we are with point‐of‐care testing [PDF]

Journal of Viral Hepatitis, 2015
SummaryViral hepatitis claims one million lives each year. Scaling up treatment for hepatitis B and C in resource‐limited settings is not possible without access to reliable diagnostic tools. This article gives an overview of current technologies and the pipeline for easy‐to‐use assays for serological and virological analyses, which can be performed at
openaire   +2 more sources

'Point-of-care' D-dimer testing [PDF]

Journal of Medical Biochemistry, 2010
D-dimer testing is efficient in the exclusion of venous thromboembolism (VTE). D-dimer laborator y assays are predominantly performed in centralised laboratories in intra-hospital settings although most patients with suspected VTE are presented in ...
Antović Jovan P.
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Development of point-of-care testing devices to improve clozapine prescribing habits and patient outcomes

Neuropsychiatric Disease and Treatment, 2019
Shamir N Kalaria,1 Deanna L Kelly21Center for Translational Medicine, University of Maryland School of Pharmacy, Baltimore, MD, USA; 2Department of Psychiatry, School of Medicine, Maryland Psychiatric Research Center, University of Maryland School of ...
Kalaria SN, Kelly DL
doaj  

Capillary-driven flow microfluidics combined with smartphone detection: an emerging tool for point-of-care diagnostics

, 2020
Point-of-care (POC) or near-patient testing allows clinicians to accurately achieve real-time diagnostic results performed at or near to the patient site.
Syed Z. J. Zaidi, Zaidi, Syed Z J, Bokhari, habib, Zhang, Xunli, Tariq, Aamira, Sammer-ul Hassan, Zobia Noreen, Donia, Ahmed, Hassan, Sammer-Ul, Noreen, Zobia, Habib Bokhari, Xunli Zhang, Aamira Tariq, Ahmed Donia   +13 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source