Results 81 to 90 of about 168,992,924 (249)

Development of point-of-care testing devices to improve clozapine prescribing habits and patient outcomes

Neuropsychiatric Disease and Treatment, 2019
Shamir N Kalaria,1 Deanna L Kelly21Center for Translational Medicine, University of Maryland School of Pharmacy, Baltimore, MD, USA; 2Department of Psychiatry, School of Medicine, Maryland Psychiatric Research Center, University of Maryland School of ...
Kalaria SN, Kelly DL
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Point-of-care testing in the cardiovascular operating theatre [PDF]

, 2006
Point-of-care testing (POCT) remains under scrutiny by healthcare professionals because of its ill-tried, young history. POCT methods are being developed by a few major equipment companies based on rapid progress in informatics and nanotechnology. Issues
Gygax, Erich, Nydegger, Urs E, Carrel, Thierry   +2 more
core   +2 more sources

Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism

, 2022
Introduction: Thrombotic complications, such as pulmonary embolism, are common in COVID-19 patients. Point-of-care ultrasound is a highly recommended tool for orientation in critically ill patients with suspected or confirmed complications.
Andrea Manojlovic, Rajovic, Nina, Novica Nikolic, Lidija Memon, Mrda, Davor, Zoran Todorovic, Todorovic, Zoran, Popadic, Viseslav, Tijana Radonjic, Ninkovic, Nebojsa, Sasa Rajsic, Ivankovic, Tatjana, Viseslav Popadic, Natasa Milic, Radonjic, Tijana, Nebojsa Ninkovic, Marija Zdravkovic, Popovic, Maja, Nikolic, Novica, Brajkovic, Milica, Memon, Lidija, Brankovic, Marija, Aleksandra Radojevic, Tatjana Ivankovic, Zdravkovic, Marija, Marija Brankovic, Maja Popovic, Lasica, Ratko, Nina Rajovic, Milic, Natasa, Manojlovic, Andrea, Radojevic, Aleksandra, Slobodan Klasnja, Ratko Lasica, Davor Mrda, Rajsic, Sasa, Milica Brajkovic, Klasnja, Slobodan   +37 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The point-of-care testing in diabetology

Clinical Management Issues, 2011
In diabetic patients glucose, haemoglobin A1c, ketones, lipids, and urinary albumin monitoring allows prevention, early detection, and treatment of diabetes-related acute and chronic complications.
Elena Matteucci, Ottavio Giampietro
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Point of Care Diagnostics in the Age of COVID-19

, 2020
The recent outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated serious respiratory disease, coronavirus disease 2019 (COVID-19), poses a major threat to global public health.
Meysam Rezaei, Sareh Zhand, Nima Sayyadi, Majid Ebrahimi Warkiani, Sajad Razavi Bazaz, Dayong Jin, Martin P. Stewart   +6 more
core   +1 more source

The use of point of care gastric ultrasound and anesthesia management in pediatric patients with preoperative fasting non-adherence scheduled for elective surgical procedures: a retrospective study

BMC Anesthesiology
Background Failure to adhere to perioperative fasting requirements increases aspiration risk and can lead to delay or cancellation of surgery. Point of care gastric ultrasound may guide decision-making to delay, cancel or proceed with surgery.
Marc D. Mecoli, Kirti Sahu, Joseph W. McSoley, Lori A. Aronson, Suryakumar Narayanasamy   +4 more
doaj   +1 more source