Results 201 to 210 of about 2,456,337 (301)

Challenges in Diagnosing Post-COVID Pneumonia in Kazakhstan - The Role of Point-of-Care Testing: A Letter to the Editor. [PDF]

Iran J Med Sci
Ablakimova N, Rachina S, Smagulova G, Mussina A, Sakhanova S, Smagulova D, Kozhantayeva S, de Silva HR.   +7 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Urinary carbonic anhydrase 1 excretion is a marker of hemolysis-triggering conditions suitable for point-of-care testing.

Blood Glob Hematol
Hulikova A, Wang Z, Broomfield H, Robinson J, Healy M, Figueroa-Mujíca RJ, Gamboa D, Torres K, Ammanath G, Hartono D, Siow RC, Engledow S, Srinamon K, Ghose A, Plewes K, Dondorp AM, Roy NBA, Villafuerte FC, Khan H, Swietach P.   +19 more
europepmc   +1 more source

Assessment of cardiac biomarker "point-of-care" testing as postmortem diagnostic tool. [PDF]

Int J Legal Med
Federspiel JM, Kettner M, Potente S, Heinbuch S, Lux C, Verhoff MA, Ramsthaler F.   +6 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Acceptability and adoption of a multiparameter point-of-care testing (POCT) device in primary healthcare for non-communicable diseases in resourced-limited communities in Peru. [PDF]

BMJ Open
Huayanay-Espinoza CA, Morán D, Albitres-Flores L, Bernabe-Ortiz A, Cahuana-Hurtado L, Vetter B, Safary E, Lazo-Porras M.   +7 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

A point-of-care testing device for monkeypox virus integrating recombinase polymerase amplification and lateral flow assay. [PDF]

BMC Med
Yu J, Di B, Zhou L, Zhao Y, Zhang D, Hong W, Cao L, Liang H, Jia H, Gu B.   +9 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source