Results 211 to 220 of about 811,999 (309)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Point-of-care testing to strengthen sexually transmitted infection case management in resource-constrained settings. [PDF]

Sex Transm Infect
Peters RPH, Manguro G, Ong'wen PA, Mdingi MM, Applegate TL, Stuart R, Harding-Esch EM, Manabe YC, Ndowa F, Van Der Pol B.   +9 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Point-of-Care Testing of Blood Lactate. Point-of-Care Testing of Blood Lactate

Laboratoriums Medizin, 2002
openaire   +1 more source

Photonic Crystal Microarray-Assisted Point-of-Care Testing for Rapid and Convenient Detection of Microalbuminuria. [PDF]

ACS Omega
He X, Zhang Y, Chen J, Li M, Chen H, Wang X, Wang Z, Zhang J, Wu Z, Cheng Q, Su M, Chen L, Liu Y, Ao Q.   +13 more
europepmc   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Smartphone-Based Peptide Nucleic Acid (PNA) Probe-Assisted Potentiometric Biosensor for Point-of-Care Testing of SARS-CoV-2 Nucleic Acid. [PDF]

Anal Chem
Ozer T, Jampasa S, Lomae A, Ruecha N, Sagdic O, Vilaivan T, Henry CS, Chailapakul O.   +7 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Managing maternity: Moving care, not patients, using artificial intelligence (AI), internet-of-things (IOT) and point-of-care testing (POCT) devices. [PDF]

Int J Gynaecol Obstet
Foo L, Choolani M, Papageorghiou A, Divakar H, Shehata H, Melamed N, Jones G, Senikas V, Van der Beek EM, Palshetkar N, Saccone G, Berghella V, Konje J, Bhatt B, Cam A, Obimbo M, Kihara AB, Hod M.   +17 more
europepmc   +1 more source