Results 91 to 100 of about 2,725,205 (348)

Staying the course: retention and participation in on-line learning in Singapore and the UK [PDF]

open access: yes, 2002
In 2001 the Singapore Institute of Management (SIM) in collaboration with the British Open University (OU) ran a successful presentation of the Level 1 Technology Course 'You, Your Computer and the Net'. The 30 point foundation level course was delivered
Herman, Clem
core  

The Impact of Coronavirus on Vermonters Experiencing Food Insecurity [PDF]

open access: yes, 2020
Key Findings 1. Respondents experiencing food insecurity were more likely to be people of color, female, live in households with children, and live in larger households. 2.
Bertmann, Farryl   +5 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Analysis Of The Relevance Of Models, Influencing Factors And The Point In Time Of The Forecast On The Prediction Quality In Order-Related Delivery Time Determination Using Machine Learning

open access: yesProceedings of the Conference on Production Systems and Logistics
One of the main objectives of manufacturing companies that structure their manufacturing system according to the workshop principle is to meet the delivery dates communicated to the customer. One approach to avoid large delivery time buffers to stabilize
Rokoss, Alexander   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The multidriver: A reliable multicast service using the Xpress Transfer Protocol [PDF]

open access: yes
A reliable multicast facility extends traditional point-to-point virtual circuit reliability to one-to-many communication. Such services can provide more efficient use of network resources, a powerful distributed name binding capability, and reduced ...
Dempsey, Bert J.   +2 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

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