Results 91 to 100 of about 8,687,208 (379)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A novel method to search for point sources of ultra-high energy neutral particles using spacetime information [PDF]

, 2023
Miguel A. Martins, Lorenzo Cazon, R. Conceição, Jaime Álvarez-Muñiz, E. Zas   +4 more
openalex   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Least-Squares Finite Element Method for Solving Stokes Flow under Point Source Magnetic Field [PDF]

, 2022
Alia Rafiza Che Ayob, Zuhaila Ismail, Erwan Hafizi Kasiman   +2 more
openalex   +1 more source

Test method for telescopes using a point source at a finite distance [PDF]

A test method for telescopes that makes use of a focused ring formed by an annular aperture when using a point source at a finite distance is evaluated theoretically and experimentally.
Griner, D. B., Korsch, D., Zissa, D. E.
core   +1 more source

Development of a GPU-based Monte Carlo dose calculation code for coupled electron-photon transport

, 2010
Monte Carlo simulation is the most accurate method for absorbed dose calculations in radiotherapy. Its efficiency still requires improvement for routine clinical applications, especially for online adaptive radiotherapy.
Amitava Majumdar, Bielajew A F Hirayama H Nelson W R Rogers D W O, Briesmeister J F, Dongju Choi, Gu X, Gu X, Jacques R Taylor R Wong J McNutt T, Josep Sempau, Lensch H Strzodka R, Li J S, Li M, Ma C M, Men C, Nelson W R Hirayama H Rogers D W O, NVIDIA, Salvat F Fernández-Varea J M Baró J Sempau J, Salvat F Fernández-Varea J M Sempau J, Sempau J, Sharp G C, Steve B Jiang, Woodcock E Murphy T Hemmings P Longworth S, Xu F, Xuejun Gu, Xun Jia, Yan G R   +24 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A Semianalytical Method of Frequency-average Smearing for Radio Interferometers based on Point Source

The Astronomical Journal
Next-generation radio interferometers, with their enhanced spatial, temporal, and high-frequency resolution, will pose considerable challenges to data processing and storage. Frequency averaging reduces the volume of data, but would cause smearing of the
Weijie Liang, Yangfan Xie, Feng Wang, Hui Deng, Ying Mei, Yunjin Zhu, Shoulin Wei   +6 more
doaj   +1 more source

Catalog Extraction in SZ Cluster Surveys: a matched filter approach

, 2006
We present a method based on matched multifrequency filters for extracting cluster catalogs from Sunyaev-Zel'dovich (SZ) surveys. We evaluate its performance in terms of completeness, contamination rate and photometric recovery for three representative ...
Angulo, Barbosa, Bartelmann, Benson, Bertin, Blanchard, Borys, Carlstrom, Colafrancesco, Cole, da Silva, Diego, Eisenstein, Eke, Freedman, Haehnelt, Haiman, Herranz, Herranz, Hobson, Holder, Hu, Huetsi, J. Delabrouille, J. G. Bartlett, J.-B. Melin, Jenkins, Jones, Kneissl, Knox, Lima, Lima, Majumdar, Melin, Mohr, Motl, Oukbir, Pierpaoli, Pires, Rosati, Schulz, Schäfer, Seljak, Spergel, Vale, Waldram, Wang, Weller, White   +48 more
core   +3 more sources