Results 111 to 120 of about 8,687,208 (379)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Study on the delineation method of riverine water source protection zones in the Qujiang River Basin

open access: yesGuan'gai paishui xuebao
【Background】River-type water sources are widely distributed in China and serve as the primary source of drinking water. Over the past decades, the proportion of non-compliant water sources has decreased due to effective control of point-source pollution.
ZHANG Jing   +6 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

NUMERICAL SOLUTION TO BOUNDARY PROBLEMS FOR POISSON EQUATION BY POINTSOURCE METHOD

open access: yesAdvanced Engineering Research, 2014
The aim o f t his p a p e r is t h e e fficie n c y im p r o v e m e n t o f o n e o f t h e m o s t a d v a n c e d t e c h niq u e s o f s olvin g t h e ellip tic b o u n d a r y v alu e p r o ble m s — t h e field p oin t- s o u r c e m e t h o d d e ...
Sergey Yuryevich Knyazev   +2 more
doaj   +1 more source

Improving meson two-point functions by low-mode averaging

open access: yes, 2004
Some meson correlation functions have a large contribution from the low lying eigenmodes of the Dirac operator. The contribution of these eigenmodes can be averaged over all positions of the source.
DeGrand   +6 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A New Method for Determining Optimal Regularization Parameter in Near-Field Acoustic Holography

open access: yesShock and Vibration, 2018
Tikhonov regularization method is effective in stabilizing reconstruction process of the near-field acoustic holography (NAH) based on the equivalent source method (ESM), and the selection of the optimal regularization parameter is a key problem that ...
Yue Xiao
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sub-wavelength imaging with a left-handed material flat lens

open access: yes, 2004
We study numerically, by means of the pseudospectral time-domain method, the unique features of imaging by a flat lens made of a left-handed metamaterial that possesses the property of negative refraction.
Berenger   +22 more
core   +1 more source

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