Results 51 to 60 of about 4,541,716 (292)

Surf-zone vortices over stepped topography [PDF]

, 2004
The problem of vortical motions in the surf zone is simplified by taking the bottom topography to be piecewise flat while allowing finite-height jumps in depth between flat regions.
Johnson, ER, McDonald, NR
core  

Conservation of Total Vorticity for a 2D Stochastic Navier Stokes Equation

Advances in Mathematical Physics, 2011
We consider 𝑁 point vortices whose positions satisfy a stochastic ordinary differential equation on ℝ2𝑁 perturbed by spatially correlated Brownian noise.
Peter M. Kotelenez, Bradley T. Seadler
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Mathematical Modeling of Vortex Interaction Using a Three-Layer Quasigeostrophic Model. Part 1: Point-Vortex Approach

Mathematics, 2020
The theory of point vortices is used to explain the interaction of a surface vortex with subsurface vortices in the framework of a three-layer quasigeostrophic model.
Mikhail A. Sokolovskiy, Xavier J. Carton, Boris N. Filyushkin   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Quasi-geostrophic vortices in compressible atmospheres [PDF]

, 2005
This paper considers the effect of an exponential variation in the background density field (as exists in compressible atmospheres) on the structure and dynamics of the quasi-geostrophic system, and compares the results with the corresponding Boussinesq ...
Scott, Richard Kirkness, Dritschel, David Gerard   +1 more
core   +1 more source

LOCALIZED VORTICES IN TWO-DIMENSIONAL HYDRODYNAMIC MEDIA

East European Journal of Physics, 2015
The review covers the main achievements in the field of the dynamics of strongly localized vortices in two-dimensional hydrodynamic media. The types of point vortices and their motion equations are discussed.
V. V. Yanovsky, A. V. Tur, K. N. Kulik
doaj  

A new member of the structured light family: optical spatiotemporal vortices

Light: Science & Applications, 2023
The burgeoning growth of structured light has opened up new possibilities for harnessing the spatiotemporal coupling effects in light. Optical spatiotemporal vortices, as a subset of spatiotemporal light, have emerged as a focal point of recent research,
Fu Feng, Xiaocong Yuan
doaj   +1 more source

Brownian point vortices and dd-model

Discrete and Continuous Dynamical Systems - S, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source