Results 81 to 90 of about 91,384 (299)
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Where Is That Crater? Best Practices for Obtaining Accurate Coordinates from LROC NAC Data
The Planetary Science JournalThe Lunar Reconnaissance Orbiter Camera (LROC) Narrow Angle Camera (NAC) images and their derived products make up one of the highest-resolution and most spatially accurate data sets available for the Moon, making them a crucial resource for planners of ...
Robert V. Wagner +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Pointing North Online: Using photographs of known environments to evaluate north pointing accuracy [PDF]
, 2021 Previous research has found that cognitive maps are not consistently oriented towards north as people tend to bias their north-pointing estimates towards nearby roads (Brunyé et al., 2015).
Burte, Heather +2 more
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Gender Differences in Pointing Accuracy in Computer-Simulated 3D Mazes
, 1999 Gender differences in pointing accuracy in computer-simulated mazes were studied as a function of maze complexity and training effects. College students (primarily White) were led through mazes with different numbers of turns; at the end of each maze ...
Lawton, Carol, Morrin, Kevin A
core
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Chinese Journal of Mechanical EngineeringPointing mechanism is widely used in aerospace field, and its pointing accuracy and stability have high requirements. The pointing mechanism will be affected by external interference when it works.
Sen Wang +5 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source