Results 61 to 70 of about 2,491,773 (298)

Disturbance Attenuation and Pointing Control System Design for an Improved Disturbance-Free Payload Spacecraft

open access: yesAerospace, 2023
The low-frequency disturbances transmitted by flexible cables are difficult to be attenuated for a novel disturbance-free payload spacecraft, which decreases the payload’s pointing accuracy and stability.
Ting Jin   +8 more
doaj   +1 more source

Accuracy of a Point-of-Care Hemoglobin A1c Assay [PDF]

open access: yesJournal of Diabetes Science and Technology, 2019
Point-of-care test (POCT) HbA1c assays provide rapidly available results for clinical decision-making. Accuracy and precision must be established. Venous blood samples from 300 patients were assayed for HbA1c by a laboratory technician (“laboratory assessment”) with the POCT Alere Afinion™ assay and a laboratory (Premier Affinity
David M. Nathan   +5 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Radiative closure tests of collocated hyperspectral microwave and infrared radiometers [PDF]

open access: yesAtmospheric Measurement Techniques
Temperature and water vapor profiles are essential to climate change studies and weather forecasting. Hyperspectral instruments are of great value for retrieving temperature and water vapor profiles, enabling accurate monitoring of their changes ...
L. Liu   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

On Orbit Demonstration of Pointing Accuracy of Ground Antennas by a Flying GEO Satellite

open access: yesSakarya University Journal of Computer and Information Sciences, 2023
Geostationary Satellites (GEO) are being used commonly in communication market. The service providers uplink or downlink the signal by using their dedicated antennas (whether with or without tracking capability) to the GEO satellite.
Ümit Güler, Ümit Cezmi Yılmaz
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

A deep learning approach for predicting the antenna pointing error caused by transmission faults with simulation data

open access: yesScientific Reports
Reflector antenna has been widely used in deep space exploration, radar warning, and other fields, all of which requires high pointing accuracy. The antenna elevation bearings are the key component that guarantees its pointing accuracy, while any ...
Lihui Chen   +5 more
doaj   +1 more source

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