Results 51 to 60 of about 91,384 (299)
High-precision pointing is a key technology in free-space optical communication, as it improves the acquisition probability and reduces the acquisition time.
Chao Peng +7 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
An automated method for the evaluation of the pointing accuracy of Sun-tracking devices [PDF]
The accuracy of solar radiation measurements, for direct (DIR) and diffuse (DIF) radiation, depends significantly on the precision of the operational Sun-tracking device.
D. J. Baumgartner +5 more
doaj +1 more source
The low-frequency disturbances transmitted by flexible cables are difficult to be attenuated for a novel disturbance-free payload spacecraft, which decreases the payload’s pointing accuracy and stability.
Ting Jin +8 more
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Radiative closure tests of collocated hyperspectral microwave and infrared radiometers [PDF]
Temperature and water vapor profiles are essential to climate change studies and weather forecasting. Hyperspectral instruments are of great value for retrieving temperature and water vapor profiles, enabling accurate monitoring of their changes ...
L. Liu +6 more
doaj +1 more source
On Orbit Demonstration of Pointing Accuracy of Ground Antennas by a Flying GEO Satellite
Geostationary Satellites (GEO) are being used commonly in communication market. The service providers uplink or downlink the signal by using their dedicated antennas (whether with or without tracking capability) to the GEO satellite.
Ümit Güler, Ümit Cezmi Yılmaz
doaj +1 more source
Accuracy measures for evaluating computer pointing devices [PDF]
In view of the difficulties in evaluating computer pointing devices across different tasks within dynamic and complex systems, new performance measures are needed. This paper proposes seven new accuracy measures to elicit (sometimes subtle) differences among devices in precision pointing tasks.
I. Scott MacKenzie +2 more
openaire +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source

