Results 81 to 90 of about 39,675 (239)
Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction
Advanced Science, EarlyView.This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng +12 more
wiley +1 more source
2021 Annual Report of the Kansas Poison Control Center at The University of Kansas Health System. [PDF]
Kans J Med, 2023 Thornton SL +4 more
europepmc +1 more source
Advanced Science, EarlyView.Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu +8 more
wiley +1 more source
Snakebite injuries in Hong Kong: A 10‐year review
Hong Kong Journal of Emergency MedicineBackground Snakebite envenomation is a priority neglected tropical disease according to the World Health Organization. To address the issue, enhanced epidemiological evidence in endemic countries and an improved availability of snake antivenoms were ...
Shan Liu, Chi Keung Chan, Man Li Tse
doaj +1 more source
Advanced Science, EarlyView.A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen +15 more
wiley +1 more source
Advanced Science, EarlyView.Multimetal Prussian blue analogues (PBAs) are converted by low‐temperature Ar annealing into a cavity/CN‐vacancy architecture that triggers in situ Ni exsolution, creating dense Ni‐PBA interfacial motifs. These motifs optimize water dissociation and H* adsorption in alkaline media, delivering markedly accelerated HER kinetics and long‐term stability ...
Shiqi Wang +5 more
wiley +1 more source
Advanced Science, EarlyView.Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang +10 more
wiley +1 more source
Bibliometric and visual analysis of in vitro-in vivo extrapolation in risk assessment
环境与职业医学BackgroundIn vitro-in vivo extrapolation (IVIVE) is an approach utilizing in vitro experimental data to predict in vivo phenomena. It is a promising tool for chemical risk assessment.ObjectiveTo learn the hotspots, evolution path, and trend of IVIVE in ...
Yulu HU +4 more
doaj +1 more source
Bipolar Palladium Membrane Enabling Crossover‐Free Selective Proton Transport
Advanced Science, EarlyView.This study introduces a crossover‐free bipolar palladium membrane that transports protons selectively via reversible Pd/PdHx absorption–desorption and lattice hydrogen diffusion, overcoming the conductivity–selectivity trade‐off of polymer membranes. It enables water‐fed Li‐mediated ammonia synthesis, achieving 51% Faradaic efficiency and stable 12 h ...
Jiyeon Baek +11 more
wiley +1 more source