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Commentary on: Attafi IM, Albeishy MY, Oraiby ME, Khardali IA, Shaikhain GA, Fageeh MM. Postmortem Distribution of Cathinone and Cathine in Human Biological Specimens in a Case of Death Associated wit [PDF]

Arab Journal of Forensic Sciences & Forensic Medicine, 2019
The interpretation of post-mortem human tissue toxicology levels may be affected by the sampling site chosen. It is important to bear this in mind when looking at the psychoactive constituents of khat (Catha edulis Forsk) that have been consumed and have
John M. Corkery, Fabrizio Schifano, Amira Guirguis   +2 more
doaj   +4 more sources

Preparative HPLC for large scale isolation, and salting-out assisted liquid–liquid extraction based method for HPLC–DAD determination of khat (Catha edulis Forsk) alkaloids

Chemistry Central Journal, 2017
Background Khat (Catha edulis Forsk) is an evergreen shrub of the Celastraceae family. It is widely cultivated in Yemen and East Africa, where its fresh leaves are habitually chewed for their momentary pleasures and stimulation as amphetamine-like ...
Minaleshewa Atlabachew, Bhagwan Singh Chandravanshi, Mesfin Redi-Abshiro   +2 more
doaj   +1 more source

The pharmacology and toxicology of the stimulant khat

Saudi Journal for Health Sciences
Khat chewing has a long history in the culture and society of the Horn of Africa and Yemen. Extracts of leaves from khat have similar actions to that of amphetamines and contain the major psychostimulant cathinone, but also the mainly peripherally acting
Hadeel A. Alsufyani
doaj   +1 more source

Sleep disturbances and memory impairment among pregnant women consuming khat: An under-recognized problem

Annals of Thoracic Medicine, 2017
Khat (Catha edulis) is a evergreen flowering shrub that is cultivated at high altitudes, especially in East Africa and the southwest of the Arabian Peninsula.
Md. Dilshad Manzar, Mohammed Salahuddin, Peter Sony, Tarekegn Tesfaye Maru, Seithikurippu R Pandi-Perumal, Adam Moscovitch, Ahmed S Bahammam   +6 more
doaj   +1 more source

Cation-exchange solid-phase and liquid-liquid extraction for the determination of khat alkaloids by reversed phase HPLC-DAD

Bulletin of the Chemical Society of Ethiopia, 2015
Leaves of khat (Catha edulis) are masticated to elicit their psycho-stimulating properties, resulting from the presence of the phenylpropylamino alkaloids.
M. Atlabachew, S. Combrinck, R. I. McCrindle   +2 more
doaj   +1 more source

Psychopharmacological aspects of catha edulis (khat) and consequences of long term use: a review

Psychiatry and Behavioral Sciences, 2011
Catha edulis (khat) is a plant grown commonly in the horn of Africa. Its leaves are chewed by the local people for their stimulant action. The purpose of this review was to summarize the psychopharmacologic aspects of Catha edulis (khat) and consequences
Nasir Tajure Wabel
doaj   +1 more source

Scientific Opinion on safety evaluation of Ephedra species for use in food

EFSA Journal, 2013
The ANS Panel provides a scientific opinion evaluating the safety in use of Ephedra herb and its preparations originating from Ephedra species when used in food, e.g. in food supplements.
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)
doaj   +1 more source

Occupational dermatological risks from bioactive compounds in Catha edulis (C. edulis): a GC–MS and cross-sectional study in Embu County, Kenya

Bulletin of the National Research Centre
Catha edulis (C. edulis) is a psychostimulant plant widely cultivated in Eastern Africa, notably valued for its economic contribution. While its primary alkaloids, cathinone and cathine, are well-documented, limited research exists on its broader ...
Richard Mwaniki Njue, Charles Mburu, Paul Njogu, Cecilia Kathurima, Jane Mburu   +4 more
doaj   +1 more source

A narrative review of preclinical evidence on the effects of Catha edulis on spatial cognition and memory in rodents

Discover Toxicology
Background Catha edulis (khat) is a stimulant plant endemic to East Africa and the Arabian Peninsula, widely consumed for its psychostimulant effects, which are primarily attributed to cathinone and cathine.
Khalid Bekri, Alfoalem Araba Abiye
doaj   +1 more source

Clavulanic Acid Improves Memory Dysfunction and Anxiety Behaviors through Upregulating Glutamatergic Transporters in the Nucleus Accumbens of Mice Repeatedly Exposed to Khat Extract. [PDF]

Int J Mol Sci, 2023
Arab AO, Alasmari F, Albaker AB, Alhazmi HA, Alameen AA, Alagail NM, Alwaeli SA, Rizwan Ahamad S, AlAsmari AF, AlSharari SD.   +9 more
europepmc   +1 more source