Results 1 to 10 of about 2,134 (194)

Observation of Hyperpositive Non-Linear Effect in Asymmetric Organozinc Alkylation in Presence of N-Pyrrolidinyl Norephedrine [PDF]

open access: yesMolecules, 2022
Phenomena related to asymmetric amplification are considered to be key to understanding the emergence of homochirality in life. In asymmetric catalysis, theoretical and experimental models have been studied to understand such chiral amplification, in ...
Thibault Thierry   +2 more
doaj   +2 more sources

Enantioselective Quantification of Amphetamine and Metabolites in Serum Samples: Forensic Evaluation and Estimation of Consumption Time [PDF]

open access: yesMetabolites, 2021
In forensic toxicology, amphetamine intoxications represent one of the most common case groups and present difficult questions for toxicologists. Estimating the time of consumption and the current influence of the stimulant is particularly difficult when
Moritz Losacker   +7 more
doaj   +2 more sources

Khat, a Cultural Chewing Drug: A Toxicokinetic and Toxicodynamic Summary [PDF]

open access: yesToxins, 2022
Khat (Catha edulis) is a recreational, chewed herbal drug that has been used as a psychostimulant for centuries in East Africa and the Arabian Peninsula, namely in Somalia, Ethiopia, and Yemen.
Bárbara Silva   +5 more
doaj   +2 more sources

Synthesis of some quinazolinones inspired from the natural alkaloid L-norephedrine as EGFR inhibitors and radiosensitizers [PDF]

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
A set of quinazolinones synthesized by the aid of L-norephedrine was assembled to generate novel analogues as potential anticancer and radiosensitizing agents.
Mostafa M. Ghorab   +3 more
doaj   +2 more sources

Correction: Thierry et al. Observation of Hyperpositive Non-Linear Effect in Asymmetric Organozinc Alkylation in Presence of N-Pyrrolidinyl Norephedrine. Molecules 2022, 27, 3780 [PDF]

open access: yesMolecules
The authors wish to make the following correction to their paper [...]
Thibault Thierry   +2 more
doaj   +2 more sources

Yangke powder alleviates OVA-induced allergic asthma by inhibiting the PI3K/AKT/NF-κB signaling pathway [PDF]

open access: yesChinese Medicine
Background Asthma is a chronic inflammatory airway disease that remains inadequately controlled by existing conventional treatments. A traditional Chinese medicine (TCM) formula of Yangke powder (yǎng ké sǎn-YKS) has demonstrated potential in alleviating
Xueyan Li   +13 more
doaj   +2 more sources

A System-Level Mechanism of Anmyungambi Decoction for Obesity: A Network Pharmacological Approach

open access: yesBiomolecules, 2021
Obesity is a low-grade systemic inflammatory disease involving adipocytokines. As though Anmyungambi decoction (AMGB) showed significant improvement on obesity in a clinical trial, the molecular mechanism of AMGB in obesity remains unknown. Therefore, we
Dongyeop Jang   +3 more
doaj   +1 more source

A Rapid and Feasible 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedra Herbal Preparations

open access: yesMolecules, 2021
A highly specific and sensitive proton nuclear magnetic resonance (1H-NMR) method has been developed for the quantification of ephedrine alkaloid derivatives in Ephedra herbal commercial prescriptions.
Hsin-Yi Hung   +9 more
doaj   +1 more source

Nasal decongestants in monotherapy for the common cold [PDF]

open access: yes, 2016
Background : Many treatments for the common cold exist and are sold over-the-counter. Nevertheless, evidence on the effectiveness and safety of nasal decongestants is limited.
De Sutter, An   +4 more
core   +2 more sources

Production of Phenylacetylcarbinol via Biotransformation Using the Co-Culture of Candida tropicalis TISTR 5306 and Saccharomyces cerevisiae TISTR 5606 as the Biocatalyst

open access: yesJournal of Fungi, 2023
Phenylacetylcarbinol (PAC) is a precursor for the synthesis of several pharmaceuticals, including ephedrine, pseudoephedrine, and norephedrine. PAC is commonly produced through biotransformation using microbial pyruvate decarboxylase (PDC) in the form of
Anbarasu Kumar   +14 more
doaj   +1 more source

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