Results 1 to 10 of about 5,160 (224)

Addictive disorders and correlates in the context of chemsex practices: A French online survey [PDF]

open access: yesAddictive Behaviors Reports
Background: Existing evidence shows that chemsex practice can contribute to adverse health outcomes. However, the presence of addictive disorders based on DSM-5 criteria remains underexplored in this population.
Luca Pavirani   +5 more
doaj   +2 more sources

The Search for the Optimal Methodology for Predicting Fluorinated Cathinone Drugs NMR Chemical Shifts [PDF]

open access: yesMolecules
Cathinone and its synthetic derivatives belong to organic compounds with narcotic properties. Their structural diversity and massive illegal use create the need to develop new analytical methods for their identification in different matrices.
Natalina Makieieva   +2 more
doaj   +2 more sources

The rising wave of cathinone use in people attending harm reduction facilities: a French repeated cross-sectional study (2019–2023) [PDF]

open access: yesAddiction Science & Clinical Practice
Background In Europe, cocaine use has recently been on the rise among people who use drugs (PWUD). In parallel, cathinones, another type of psychostimulant that were once associated within the unique context of chemsex, are now spreading to broader ...
Julia de Ternay   +2 more
doaj   +2 more sources

Spectroscopic and Chromatographic Characterization of Two Isomeric Cathinone Derivatives: N-Butyl-Norbutylone and N-Ethylhexylone [PDF]

open access: yesMolecules
In this study, two isomeric cathinone derivatives, N-butyl-norbutylone and N-ethylhexylone, seized on the illicit drug market in Poland, were described and characterized by various instrumental analytical methods.
Marcin Rojkiewicz   +4 more
doaj   +2 more sources

In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5

open access: yesToxicology Reports, 2022
Cathinone is the psychostimulatory major active ingredient of khat (Catha edulis Forsk) and are often co-abused with alcohols and polydrugs. With the increased consumption of khat and cathinones on a global scale, efforts should be channelled into ...
Sharoen Yu Ming Lim   +5 more
doaj   +1 more source

Efficient flat membrane based liquid phase microextraction of cathinones from environmental water and biological samples

open access: yesTalanta Open, 2023
Cathinone drugs are one kind of new psychoactive substances, which are widely acknowledged to be harmful. Thus, rapid and efficient extraction of cathinone drugs from biological materials is of great importance in the field of forensic medicine and ...
Changbao Hong   +3 more
doaj   +1 more source

CYP Gene Expression and In Vivo Biological Effects of Khat Ethanol Extract, Cathinone and Cathine in Caenorhabditis elegans

open access: yesProgress in Microbes and Molecular Biology, 2023
The significant influence of khat, cathinone, and cathine on appetite suppression, reproduction impairment, and inhibitory effects on CYPs enzyme activity is widely recognised, but much remains unknown about its mode of action.
Sharoen Yu Ming Lim   +5 more
doaj   +1 more source

Khat chewing and cardiovascular disease

open access: yesHeart Views, 2022
Khat chewing is a deeply rooted habit in Yemen. It has social, economic, and medical problems. Chronic use of khat chewing increases the risk of many medical complications. Cathinone, the main khat leaf constituent, has an indirect sympathomimetic action.
Ahmed Al-Motarreb, Jassim AL-Suwaidi
doaj   +1 more source

Carbon dots functionalized papers for high-throughput sensing of 4-chloroethcathinone and its analogues in crime sites [PDF]

open access: yesRoyal Society Open Science, 2019
Sensitive and selective assays are demanded for quantitation of new psychoactive substances such as 4-chloroethcathinone that is a π-conjugated keto compound.
Yao-Te Yen   +4 more
doaj   +1 more source

Khat, a Cultural Chewing Drug: A Toxicokinetic and Toxicodynamic Summary

open access: yesToxins, 2022
Khat (Catha edulis) is a recreational, chewed herbal drug that has been used as a psychostimulant for centuries in East Africa and the Arabian Peninsula, namely in Somalia, Ethiopia, and Yemen.
Bárbara Silva   +5 more
doaj   +1 more source

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