Neurotoxicity induced by mephedrone: an up-to-date review [PDF]
, 2017 BACKGROUND: Mephedrone is a β-ketoamphetamine belonging to the family of synthetic cathinones, an emerging class of designer drugs known for their hallucinogenic and psychostimulant properties as well as for their abuse potential.
Busardo', FRANCESCO PAOLO +6 more
core +1 more source
Arab Journal of Forensic Sciences & Forensic Medicine, 2018 Chewing khat leaves has been associated with several adverse health effects, and there are very few case reports of cardiotoxicity, stroke and death resulting from this.
Ibraheem M. Attafi +5 more
doaj +1 more source
Herbal highs: review on psychoactive effects and neuropharmacology [PDF]
, 2017 Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S +5 more
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Evaluation of the cytotoxic and genotoxic potential of Khat (Catha edulis Forsk) extracts on human T lymphoblastoid cell line [PDF]
, 2004 This paper reports on an investigation of the cytotoxic and genotoxic potential of khat extract using a human T lymphoblastoid cell line (CEM). Exponentially growing CEM cells were cultured for 12 h in the presence of khat extract (0-2000 μg ml-1 ...
Al-Meshal +20 more
core +1 more source
Toxic effect of cathinone (an active principle of Catha edulis) on brain lipids in Swiss albino mice
Environment Conservation Journal, 2014 The leaves of khat plant (Catha edulis) are widely consumed by people of East African countries and Arabian Peninsula for their pleasurable and stimulating effects. The consumption of khat is prohibited in the Kingdom of Saudi Arabia but it is being used
Mohammed M. Safhi +7 more
doaj +1 more source
Stability of Synthetic Cathinones in Blood [PDF]
Journal of Analytical Toxicology, 2017 The synthetic cathinones are powerful psychostimulants that have been associated with impairment, intoxication and fatal overdose. Forensic laboratories must be able to identify these new drugs as part of antemortem and postmortem toxicology investigations.
Lindsay, Glicksberg, Sarah, Kerrigan
openaire +2 more sources
Analysis of Cathinone Alkaloids in Khat by HPLC-Q-TOF In-source Fragmentation Multistage Mass Spectrometry [PDF]
Zhipu XuebaoKhat is a kind of common drug plant. Many experiments have shown that the content of cathinone norpseudoephedrine and norephedrine in some varieties of Khat are similar.
SHI Hong-fei1, XU Bo-peng1, QUAN Yang-ke2, XU Cheng-xin1, ZHOU Xiu-qi1
doaj +1 more source
Comparison of six derivatizing agents for the determination of nine synthetic cathinones using gas chromatography-mass spectrometry [PDF]
, 2017 Six acylation reagents have been compared for their derivatisation potential towards nine synthetic cathinones by gas chromatography-mass spectrometry (GC-MS).
Alsenedi, Khalid A., Morrison, Calum
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Cathinone Neurotoxicity (“The “3Ms”) [PDF]
Current Neuropharmacology, 2015 Synthetic cathinones are designer drugs of the phenethylamine class, structurally and pharmacologically similar to amphetamine, 3,4-methylenedioxymethamphetamine (MDMA), cathinone and other related substances. New analogues, legal at least, until formally banned (a time consuming process), are introduced almost daily The United Nations estimates nearly
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Neuropharmacology of Synthetic Cathinones [PDF]
, 2018 Synthetic cathinones are derivatives of the naturally occurring compound cathinone, the main psychoactive ingredient in the khat plant Catha edulis. Cathinone is the β-keto analog of amphetamine, and all synthetic cathinones display a β-keto moiety in their structure.
Michael H, Baumann +3 more
openaire +2 more sources