Results 21 to 30 of about 3,347 (210)
Toxicometabolomics of cathinone derivatives [PDF]
, 2020 Die vorliegende Arbeit untersuchte den Metabolismus der synthetischen Cathinone alpha-PBP, alpha-PVT, alpha-PHP, alpha-PEP, and alpha-POP mit und ohne Metabolomik. Der Metabolismus wurde konventionell untersucht, sowie die Kinetikparameter der beteiligten Cytochrom P450 (CYP) Enzyme bestimmt.
Manier, Sascha Kevin
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Applied SciencesToday, cathinone and its synthetic derivatives are among the most popular narcotics in the world. Their different cytotoxic activities on humans are increasingly and rapidly being published in forensic reports and the scientific literature.
Natalina Makieieva +2 more
doaj +2 more sources
Spectroscopic and Chromatographic Characterization of Two Isomeric Cathinone Derivatives: N-Butyl-Norbutylone and N-Ethylhexylone [PDF]
MoleculesIn this study, two isomeric cathinone derivatives, N-butyl-norbutylone and N-ethylhexylone, seized on the illicit drug market in Poland, were described and characterized by various instrumental analytical methods.
Marcin Rojkiewicz +4 more
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The Pharmacological Profile of Second Generation Pyrovalerone Cathinones and Related Cathinone Derivative [PDF]
International Journal of Molecular Sciences, 2021 Pyrovalerone cathinones are potent psychoactive substances that possess a pyrrolidine moiety. Pyrovalerone-type novel psychoactive substances (NPS) are continuously detected but their pharmacology and toxicology are largely unknown. We assessed several pyrovalerone and related cathinone derivatives at the human norepinephrine (NET), dopamine (DAT), and
Karolina E. Kolaczynska +3 more
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Talanta Open, 2023 Cathinone drugs are one kind of new psychoactive substances, which are widely acknowledged to be harmful. Thus, rapid and efficient extraction of cathinone drugs from biological materials is of great importance in the field of forensic medicine and ...
Changbao Hong +3 more
doaj +1 more source
Progress in Microbes and Molecular Biology, 2023 The significant influence of khat, cathinone, and cathine on appetite suppression, reproduction impairment, and inhibitory effects on CYPs enzyme activity is widely recognised, but much remains unknown about its mode of action.
Sharoen Yu Ming Lim +5 more
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Khat chewing and cardiovascular disease
Heart Views, 2022 Khat chewing is a deeply rooted habit in Yemen. It has social, economic, and medical problems. Chronic use of khat chewing increases the risk of many medical complications. Cathinone, the main khat leaf constituent, has an indirect sympathomimetic action.
Ahmed Al-Motarreb, Jassim AL-Suwaidi
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Carbon dots functionalized papers for high-throughput sensing of 4-chloroethcathinone and its analogues in crime sites [PDF]
Royal Society Open Science, 2019 Sensitive and selective assays are demanded for quantitation of new psychoactive substances such as 4-chloroethcathinone that is a π-conjugated keto compound.
Yao-Te Yen +4 more
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The clinical challenges of synthetic cathinones [PDF]
British Journal of Clinical Pharmacology, 2020 AimsWithin the new psychoactive substances (NPS) scenario, several hundred different molecules, mostly including synthetic cannabinoids and cathinones, have been identified so far. The aims of the paper were to: (i) identify the number of synthetic cathinones mentioned in a range of psychonaut, NPS‐related, online sources; and (ii) describe the ...
Fabrizio Schifano +7 more
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Khat, a Cultural Chewing Drug: A Toxicokinetic and Toxicodynamic Summary
Toxins, 2022 Khat (Catha edulis) is a recreational, chewed herbal drug that has been used as a psychostimulant for centuries in East Africa and the Arabian Peninsula, namely in Somalia, Ethiopia, and Yemen.
Bárbara Silva +5 more
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