Results 11 to 20 of about 3,347 (210)

Synthetic cathinone abuse

open access: yesClinical Pharmacology: Advances and Applications, 2013
Michael Capriola Thomasville Medical Center, Thomasville, NC, USA Abstract: The abuse of synthetic cathinones, widely known as bath salts, has been increasing since the mid-2000s.
Capriola M
doaj   +6 more sources

In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5

open access: yesToxicology Reports, 2022
Cathinone is the psychostimulatory major active ingredient of khat (Catha edulis Forsk) and are often co-abused with alcohols and polydrugs. With the increased consumption of khat and cathinones on a global scale, efforts should be channelled into ...
Sharoen Yu Ming Lim   +5 more
doaj   +3 more sources

Cathinone Use Disorder in the Context of Slam Practice: New Pharmacological and Clinical Challenges

open access: yesFrontiers in Psychiatry, 2020
Background“Slam” has emerged since 2008 as a new international phenomenon among men who have sex with men (MSM); it consists of the intravenous injection of drugs before or during planned sexual activity.
Benoit Schreck   +12 more
doaj   +2 more sources

Analysis of Cathinone Alkaloids in Khat by HPLC-Q-TOF In-source Fragmentation Multistage Mass Spectrometry [PDF]

open access: yesZhipu Xuebao
Khat is a kind of common drug plant. Many experiments have shown that the content of cathinone norpseudoephedrine and norephedrine in some varieties of Khat are similar.
SHI Hong-fei1, XU Bo-peng1, QUAN Yang-ke2, XU Cheng-xin1, ZHOU Xiu-qi1
doaj   +2 more sources

Postmortem Distribution of Cathinone and Cathine in Human Biological Specimens in a Case of Death Associated with Khat Chewing [PDF]

open access: yesArab Journal of Forensic Sciences & Forensic Medicine, 2018
Chewing khat leaves has been associated with several adverse health effects, and there are very few case reports of cardiotoxicity, stroke and death resulting from this.
Ibraheem M. Attafi   +5 more
doaj   +2 more sources

Metabolism of cathinone to (−)-norephedrine and (−)-norpseudoephedrine

open access: yesJournal of Pharmacy and Pharmacology, 1986
Abstract S-(−)-Cathinone (S-(−)-α-aminopropiophenone) is the major active principle of khat leaves (Catha edulis), which are widely used in East Africa and the Arab peninsula as an amphetamine-like stimulant. After oral administration of synthesized cathinone (isomers, racemate), 22–52% was recovered in 24 h urine samples mainly as ...
R, Brenneisen   +2 more
openaire   +3 more sources

Experimental 1H, 13C and T1 NMR Studies of Graphene Oxide Interactions with 2-Fluorophenylacetic Acid as a Fluorinated Cathinone Model Supported by Molecular Modelling [PDF]

open access: yesMolecules
Cathinone and its synthetic derivatives are among the most popular drugs worldwide. However, the literature provides data on the medicinal and cytotoxic potential of some of these compounds.
Natalina Makieieva   +3 more
doaj   +2 more sources

Cyclodextrin-Enabled Enantioselective Complexation Study of Cathinone Analogs

open access: yesMolecules
The characteristic alkaloid component of the leaves of the catnip shrub (Catha edulis) is cathinone, and its synthetic analogs form a major group of recreational drugs. Cathinone derivatives are chiral compounds. In the literature, several chiral methods
András Dohárszky   +4 more
doaj   +2 more sources

Isolation, Characterization, and Stability Assessment of Pure Enantiomers of Cathinone Derivatives via Semi-Preparative HPLC-UV Using a Phenomenex Lux® 5 Column [PDF]

open access: yesMolecules
In addition to well-known traditional synthetic illicit drugs like cocaine, amphetamines, and heroin, an increasing number of new psychoactive substances (NPS) are appearing on the global drug market.
Stefanie Handl   +3 more
doaj   +2 more sources

The rising wave of cathinone use in people attending harm reduction facilities: a French repeated cross-sectional study (2019–2023) [PDF]

open access: yesAddiction Science & Clinical Practice
Background In Europe, cocaine use has recently been on the rise among people who use drugs (PWUD). In parallel, cathinones, another type of psychostimulant that were once associated within the unique context of chemsex, are now spreading to broader ...
Julia de Ternay   +2 more
doaj   +2 more sources

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