Results 41 to 50 of about 1,089 (139)

STEREOSELECTIVE RADICAL-MEDIATED CYCLIZATION OF NOREPHEDRINE DERIVED ALPHA-IODOAMIDES - EXPERIMENTS AND TS-MODELING

open access: yes, 1991
Radical-mediated cyclization of norephedrine derived alpha-iodoamides 1 was found to be highly stereoselective (greater-than-or-equal-to 97:3) favouring diastereoisomer 2.
Marco Vassallo   +7 more
core   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra   +2 more
wiley   +1 more source

Metabolism of cathinone to (−)-norephedrine and (−)-norpseudoephedrine

open access: yes, 1986
S-(−)-Cathinone (S-(−)-α-aminopropiophenone) is the major active principle of khat leaves (Catha edulis), which are widely used in East Africa and the Arab peninsula as an amphetamine-like stimulant.
S Geisshüsler, X Schorno, R Brenneisen
core   +1 more source

Mechanistic pharmacokinetic modelling of ephedrine, norephedrine and caffeine in healthy subjects

open access: yes, 2005
AIM: The combination of ephedrine and caffeine has been used in herbal products for weight loss and athletic performance-enhancement, but the pharmacokinetic profiles of these compounds have not been well characterized.
Haller, CA   +3 more
core   +1 more source

Effect of Intramolecular Hydrogen Bonds on the Binding Efficiency of Compounds Containing Aminoalcohol‐Based Subunits in Combination with Heterocyclic Groups

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 29, 7 August 2026.
This study broadens our understanding of the role of intramolecular interactions in molecular recognition and highlights the importance of considering their formation when designing artificial receptors, new drugs, and related systems. Aminoalcohols represent an important class of compounds and serve as building blocks for numerous biologically active ...
Manuel Stapf, Monika Mazik
wiley   +1 more source

Stereoisomeric Identification of Norephedrine Derived from Methamphetamine or Amphetamine:  Urinalysis Results of 33 Methamphetamine Abusers and 1 Amphetamine Abuser in Japan

open access: yes, 2016
Stereoisomeric identification of norephedrine (NE) derived from methamphetamine (MA) or amphetamine (AM) was investigated by SIM-GC/MS assay using the urine of 33 MA abusers and 1 AM abuser.
Masahito Kido (2489719)   +7 more
core   +5 more sources

Health, Social and Recidivism Outcomes Among People Who Have Been Incarcerated in New South Wales, Australia: Study Protocol and Cohort Profile for the Prison Outcomes STudy (POST)

open access: yesDrug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction We have been funded to examine post‐incarceration health and social outcomes for all people incarcerated in New South Wales, Australia, 2000–2022; assess treatment and services for drug dependence and serious mental illness; and project the impact of expanding intervention coverage. We will use a linked cohort, the Prison Outcomes
Louisa Degenhardt   +19 more
wiley   +1 more source

Cathine and norephedrine, both phenylpropanolamines, accelerate capacitation and then inhibit spontaneous acrosome loss

open access: yes, 2005
BACKGROUND: Cathinone, released when Catha edulis leaves (khat) are chewed, has euphoric, stimulatory properties. It is metabolized to the phenylpropanollamines (PPAs) cathine and norephedrine.
Lynn R. Fraser   +3 more
core   +1 more source

Metabolic N- and α-C-oxidation of norephedrine by rabbit liver microsomal fractions and synthesis of the metabolic products

open access: yes, 1974
The products of metabolism of norephedrine by 10 000 g fractions of rabbit liver microsomes have been shown to be norephedrine hydroxylamine, l-hydroxy-2-oxo-l-phenylpropane oxime, 1-hydroxy-2-oxo-1-phenylpropane, 1,2-dihydroxy-l-phenylpropane (erythro).
G R Jones, D S Al-Sarraj, A H Beckett
core   +1 more source

Combination of a UPO‐Based Epoxidation With a Subsequent Ring‐Opening Reaction for the Synthesis of Amino Alcohols

open access: yesChemBioChem, Volume 27, Issue 5, 13 March 2026.
The synthesis of aromatic amino alcohols via a combination of an unspecific peroxygenase‐catalysed reaction, oxyfunctionalization, and addition of selected nucleophiles and electrophiles in a highly atom‐efficient manner was investigated. This study presents the design to aim for an atom‐efficient chemo‐enzymatic synthesis route towards aromatic amino ...
Simon Last   +3 more
wiley   +1 more source

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