Results 61 to 70 of about 2,134 (194)

Recent Progress in the Synthesis of α‐Hydroxy Carbonyl Compounds with ThDP‐dependent Carboligases

open access: yesChemCatChem, Volume 16, Issue 15, August 12, 2024.
Building carbon connections: ThDP‐dependent carboligases are biocatalysts for the (asymmetric) synthesis of α‐hydroxy‐carbonyl compounds. In this review article we summarize recent progress on structural characterization and application of carboligases for single‐ and multi‐step reactions.
Hana Dobiašová   +3 more
wiley   +1 more source

Population kinetic/pharmacodynamic modelling of the haemodynamic effects of cafedrine/theodrenaline (Akrinor) under general anaesthesia

open access: yesBritish Journal of Clinical Pharmacology, Volume 90, Issue 8, Page 1964-1974, August 2024.
Abstract Aims The 20:1 combination of cafedrine and theodrenaline (C/T) is widely used in Germany for the treatment of arterial hypotension. Since there is little knowledge about the impact of covariates on the effect, the aim was to develop a kinetic/pharmacodynamic covariate model describing mean arterial pressure (MAP), systolic (SBP) and diastolic ...
Christiane Dings   +8 more
wiley   +1 more source

Development of stimuli-responsive smart hydrogels using molecular imprinting and interpenetrating polymer networks [PDF]

open access: yes, 2014
Different classes of stimuli-responsive smart hydrogels (SRSH) were synthesized in order to assess the usefulness of molecular imprinting and generation of interpenetrating polymer networks to obtain advanced materials with tailored properties ...
Costa, Mário Rui   +5 more
core  

Physiological and Pharmacokinetic Effects of Oral 1,3-Dimethylamylamine Administration in Men [PDF]

open access: yes, 2013
BACKGROUND: 1,3-dimethylamylamine (DMAA) has been a component of dietary supplements and is also used within "party pills," often in conjunction with alcohol and other drugs.
Bloomer, Richard   +4 more
core   +1 more source

A Powerful P−N Connection: Preparative Approaches, Reactivity, and Applications of P‐Stereogenic Aminophosphines

open access: yesChemistry – A European Journal, Volume 30, Issue 18, March 25, 2024.
New catalytic possibilities in the synthesis of P‐stereogenic aminophosphine chalcogenides and boranes serve as an expansion in addition to established methods based on chiral auxiliaries. Stereoselective transformations into valuable building blocks facilitate catalyst design for use in organocatalytic and transition metal‐based applications. Here, we
Tanja Huber, Jonathan O. Bauer
wiley   +1 more source

Catha edulis (khat) use and demographic correlates of schizophrenia: Case‐control study

open access: yesMental Health Science, Volume 2, Issue 1, Page 14-20, March 2024.
Abstract Use of Catha edulis is common among people living with schizophrenia. However, as is the case for most developing countries, the association of Catha edulis use and demographic variables to schizophrenia are not fully understood in Ethiopia.
Abraha Gosh Woldemariam   +1 more
wiley   +1 more source

Insight into the Stereoselective Synthesis of (1S)‐Nor(pseudo)ephedrine Analogues by a Two‐Steps Biocatalytic Process

open access: yesChemCatChem, Volume 16, Issue 3, February 8, 2024.
The stereodivergent synthesis of variously substituted norephedrines has been attained starting from the cheap and commercially available corresponding aromatic aldehydes through a bi‐enzymatic synthetic sequence. In the first step, a benzoin‐type condensation is mediated by the (S)‐selective acetoin:dichlorophenolindophenol oxidoreductase (Ao:DCPIP OR)
Noemi Fracchiolla   +9 more
wiley   +1 more source

Production of RAFT imprinted smart hydrogel particles in a continuous flow micro-reactor [PDF]

open access: yes, 2014
Feasibility of the production of RAFT imprinted smart hydrogel particles in continuous flow micro-reactor is here showed. Microfluidic continuous operation was combined with RAFT polymerization and molecular imprinting tecniques involving selected ...
Costa, Mário Rui   +4 more
core  

Inhaled nitric oxide in acute bronchiolitis: A systematic review and meta‐analysis

open access: yesPediatric Pulmonology, Volume 59, Issue 2, Page 426-432, February 2024.
Abstract Objective Until date there is lack of effective therapies in acute bronchiolitis in infants. The aim was to analyze inhaled nitric oxide efficacy in acute bronchiolitis. Design Systematic review and meta‐analysis of randomized controlled trials. Setting Pediatric specialized healthcare. Patients All infants (age less than 2 years) having acute
Ilari Kuitunen, Marjo Renko
wiley   +1 more source

Catalytic Asymmetric Transfer Hydrogenation of Imines: Recent Advances [PDF]

open access: yes, 2015
In this review article recent developments in the asymmetric transfer hydrogenation of imines from 2008 up to today are presented. The main methodology involves either metal-catalyzed procedures in the presence of a chiral ligand or organocatalyzed ...
Foubelo, Francisco, Yus, Miguel
core   +2 more sources

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