Results 31 to 40 of about 2,134 (194)

Metabolism of cathinone to (−)-norephedrine and (−)-norpseudoephedrine

Journal of Pharmacy and Pharmacology, 1986
Abstract S-(−)-Cathinone (S-(−)-α-aminopropiophenone) is the major active principle of khat leaves (Catha edulis), which are widely used in East Africa and the Arab peninsula as an amphetamine-like stimulant. After oral administration of synthesized cathinone (isomers, racemate), 22–52% was recovered in 24 h urine samples mainly as ...
R, Brenneisen, S, Geisshüsler, X, Schorno   +2 more
openaire   +2 more sources

Preparative HPLC for large scale isolation, and salting-out assisted liquid–liquid extraction based method for HPLC–DAD determination of khat (Catha edulis Forsk) alkaloids

Chemistry Central Journal, 2017
Background Khat (Catha edulis Forsk) is an evergreen shrub of the Celastraceae family. It is widely cultivated in Yemen and East Africa, where its fresh leaves are habitually chewed for their momentary pleasures and stimulation as amphetamine-like ...
Minaleshewa Atlabachew, Bhagwan Singh Chandravanshi, Mesfin Redi-Abshiro   +2 more
doaj   +1 more source

Detection of Drugs of Abuse by Raman Spectroscopy [PDF]

, 2011
Raman spectroscopy can provide rapid, sensitive, non-destructive analysis of a variety of drug types (e.g. amphetamines, alkaloids, designer drugs and date rape drugs). This review concentrates on developments in the past 15 years.
Ali, Ali, Ali, Angel, Anyu, Bell, Bell, Bell, Bell, Bell, Brewster, Campion, Carter, Clark, Day, Day, Edwards, Eliasson, Faulds, Frederick, Garrido, Hargreaves, Hargreaves, Harvey, Katainen, Leger, Littleford, Milhazes, Milhazes, Noonan, Noonan, Qu, Ryder, Ryder, Ryder, Sands, Schulz, Smith, Sägmüller, Thorley, Tsuchihashi, West, West, West, Weston, White   +45 more
core   +1 more source

Commentary on: Attafi IM, Albeishy MY, Oraiby ME, Khardali IA, Shaikhain GA, Fageeh MM. Postmortem Distribution of Cathinone and Cathine in Human Biological Specimens in a Case of Death Associated wit

Arab Journal of Forensic Sciences & Forensic Medicine, 2019
The interpretation of post-mortem human tissue toxicology levels may be affected by the sampling site chosen. It is important to bear this in mind when looking at the psychoactive constituents of khat (Catha edulis Forsk) that have been consumed and have
John M. Corkery, Fabrizio Schifano, Amira Guirguis   +2 more
doaj   +1 more source

Microwave-Assisted Improved Synthesis of Oxazolidin-2-ones, Oxazolidine-2-thiones and Thiazolidine-2-thione Chiral Auxiliaries

Molecules, 2011
A microwave assisted method for the synthesis of some typical 4-substituted oxazolidinone chiral auxiliaries used in asymmetric synthesis is reported in this work.
Mario Ordóñez, Rosmarbel Morales-Nava, Mario Fernández-Zertuche   +2 more
doaj   +1 more source

Formation of racemic compound crystals by mixing of two enantiomeric crystals in the solid state. Liquid transport of molecules from crystal to crystal [PDF]

, 1997
Mixing of powdered (-)- and (+)-enantiomer crystals in the solid state gives crystals of the racemic compound. This racemic crystal formation was followed by IR spectral measurement of a 1 :1 mixture of (-)- and (+)-enantiomer crystals as a Nujol mull ...
Hirotsu Ken, Koshima Hideko, Miyahara Ikuko, Miyamoto Hisakazu, Tanaka Koichi, Toda Fumio, 宮原 郁子, 宮本 久一, 小島 秀子, 広津 建, 戸田 芙三夫, 田中 耕一   +11 more
core   +2 more sources

Cation-exchange solid-phase and liquid-liquid extraction for the determination of khat alkaloids by reversed phase HPLC-DAD

Bulletin of the Chemical Society of Ethiopia, 2015
Leaves of khat (Catha edulis) are masticated to elicit their psycho-stimulating properties, resulting from the presence of the phenylpropylamino alkaloids.
M. Atlabachew, S. Combrinck, R. I. McCrindle   +2 more
doaj   +1 more source

Isolation and structural determination of non-racemic tertiary cathinone derivatives [PDF]

, 2015
The racemic tertiary cathinones N,N-dimethylcathinone (1), N,N-diethylcathinone (2) and 2-(1-pyrrolidinyl)-propiophenone (3) have been prepared in reasonable yield and characterized using NMR and mass spectroscopy. HPLC indicates that these compounds are
Bell, Steven J.E., Bouazzaoui, Samira, Coles, Simon J., Fletcher, Nick, Goodrich, Peter, Horton, Peter N., Jones, Louise E., Sheldrake, Gary N., Zhou, MengJie   +8 more
core   +1 more source

The pharmacology and toxicology of the stimulant khat

Saudi Journal for Health Sciences
Khat chewing has a long history in the culture and society of the Horn of Africa and Yemen. Extracts of leaves from khat have similar actions to that of amphetamines and contain the major psychostimulant cathinone, but also the mainly peripherally acting
Hadeel A. Alsufyani
doaj   +1 more source

Adulteration of Dietary Supplements by the Illegal Addition of Synthetic Drugs: a review [PDF]

, 2016
In the last few years, the consumption of dietary supplements, especially those having plants as ingredients, has been increasing due to the common idea that they are natural products posing no risks to human health.
Amaral, Joana S., Oliveira, Beatriz, Rocha, Tiago   +2 more
core   +1 more source