Cathine and alcohol involved fatality: A rare case report with a brief review of the literature [PDF]
Egyptian Journal of Forensic Sciences, 2016 Toxicology screening of unusual poisons is important. We report a case of death of a young female suspected to die due to drug overdose. Medico legal autopsy was indicative of cerebral hemorrhage.
Atul Bajaj, Sukhminder Kaur
exaly +5 more sources
Efficacy and Safety of Cathine (Nor-Pseudoephedrine) in the Treatment of Obesity: A Randomized Dose-Finding Study [PDF]
Obesity Facts, 2017 Objective: To investigate the efficacy and safety of increasing doses of cathine (nor-pseudoephedrine) as a weight-lowering agent in patients with obesity.
Hans Hauner +5 more
doaj +7 more sources
Fatalities Involving Khat in Jazan, Saudi Arabia, 2018 to 2021 [PDF]
Toxics, 2023 Interpreting fatalities involving khat is challenging due to a lack of data on cathinone and cathine reference concentrations in postmortem tissues. This study investigated the autopsy findings and toxicological results of fatalities involving khat in ...
Ghassan Shaikhain +11 more
doaj +3 more sources
Postmortem Distribution of Cathinone and Cathine in Human Biological Specimens in a Case of Death Associated with Khat Chewing [PDF]
Arab Journal of Forensic Sciences & Forensic Medicine, 2018 Chewing khat leaves has been associated with several adverse health effects, and there are very few case reports of cardiotoxicity, stroke and death resulting from this.
Ibraheem M. Attafi +5 more
doaj +4 more sources
Protein-Ligand Identification and In Vitro Inhibitory Effects of Cathine on 11 Major Human Drug Metabolizing Cytochrome P450s. [PDF]
Int J Toxicol, 2022 Cathine is the stable form of cathinone, the major active compound found in khat (Catha edulis Forsk) plant. Khat was found to inhibit major phase I drug metabolizing cytochrome P450 (CYP) enzyme activities in vitro and in vivo.
Lim SYM +5 more
europepmc +5 more sources
Cathine and norephedrine, both phenylpropanolamines, accelerate capacitation and then inhibit spontaneous acrosome loss [PDF]
Human Reproduction, 2005 BACKGROUND: Cathinone, released when Catha edulis leaves (khat) are chewed, has euphoric, stimulatory properties. It is metabolized to the phenylpropanollamines (PPAs) cathine and norephedrine.
Lynn R. Fraser +3 more
core +4 more sources
Khat, a Cultural Chewing Drug: A Toxicokinetic and Toxicodynamic Summary [PDF]
Toxins, 2022 Khat (Catha edulis) is a recreational, chewed herbal drug that has been used as a psychostimulant for centuries in East Africa and the Arabian Peninsula, namely in Somalia, Ethiopia, and Yemen.
Bárbara Silva +5 more
doaj +2 more sources
Catha edulis Leaves: Morphological Characterization and Anti-Inflammatory Properties in an In Vitro Model of Gastritis [PDF]
PlantsKhat leaves, indigenous to eastern Africa, have been chewed for centuries for their stimulant effects, attributed to alkaloids such as cathinone and cathine. Although associated with gastric disorders like gastritis and gastro-oesophageal reflux disease,
Andrea Magnavacca +13 more
doaj +2 more sources
Sex-specific effects of appetite suppressants on stereotypy in rats. [PDF]
PLoS ONEThis study investigated the sex-specific effects of commonly prescribed appetite suppressants on body weight and the manifestation of motor side effects, specifically stereotypy.
Axl Lopez +2 more
doaj +2 more sources
Progress in Microbes and Molecular Biology, 2023 The significant influence of khat, cathinone, and cathine on appetite suppression, reproduction impairment, and inhibitory effects on CYPs enzyme activity is widely recognised, but much remains unknown about its mode of action.
Sharoen Yu Ming Lim +5 more
doaj +2 more sources