Results 121 to 130 of about 60,059 (301)

A Triage for Disposition of Poisoned Patients with Cardiovascular Therapeutic Agents Presented to Poison Control Center of Ain Shams University Hospitals [PDF]

, 2022
Ahmed Omar, Seham Fouad Abdelaal, Hanan Salem   +2 more
openalex   +1 more source

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun, Jie Liu, E Xiang, Xia Li, Xuerong Yan, Yuxi Wang, Feng Li, Hao Kou, Hui Wang, Yu Guo   +9 more
wiley   +1 more source

Selective and Long‐Term Stable Ammonia Electrolysis Using Pt–WOx Catalysts with Suppressed NOx Formation and Enhanced Activity

Advanced Science, EarlyView.
This study reports photodeposited Pt nanoparticles on WOx nanowires (Pt–WOx (P)) as a bifunctional catalyst for ammonia electrolysis. Strong metal–support interactions promote electron transfer to Pt, lowering the energy barrier of the rate‐determining step and suppressing NOx formation.
Changhyun Lim, Hyogyun Roh, Hyeon Kim, Dayoung Kwon, Okkyun Seo, Jiayi Tang, Takeshi Watanabe, Wooyul Kim, Donghwa Lee, Kijung Yong   +9 more
wiley   +1 more source

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source

Prevalence of anticoagulant rodenticide poisoning in France: human and animal data

Julius-Kühn-Archiv, 2011
Anticoagulant rodenticides have been used for over 50 years to control rodent populations. Since their first introduction, resistance developed in rodents, and second generation products, more active but also more toxic, have been marketed.
Berny, P., Velardo, J., Pulce, C., D’Amico, A., Kammerer, M., Lasseur, R., Belhadj, A., Mastain, O   +7 more
doaj   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Epidemiology and Clinical Characteristics of Acute Plant Exposure in Patients Aged between 0 and 18 Years—A Six-Year Retrospective Study

Children
Background: Exposure to plants accounts for approximately 5% of human poisoning cases reported by poison control centers in North America and Europe. The aim of this study was to investigate acute plant poisoning in patients aged 0–18 years admitted to a
Gabriela Viorela Nițescu, Andreea Grama, Teodora Turcu, Andreea Strătulă, Ana Dragomirescu, Elena Silvia Pană, Andreea Baciu, Daniela Luiza Baconi, Maria Dorina Crăciun, Coriolan Emil Ulmeanu   +9 more
doaj   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

Catastrophic Degradation in Solid Oxide Fuel Cells Caused by Air Supply Interruption in Real‐World Operations: Fundamental Mechanisms and Mitigation Strategies

Advanced Science, EarlyView.
Interrupting the air supply during the operation of solid oxide fuel cells leads to irreversible chemical degradation of the cathode materials, primarily driven by strontium at the A‐site of perovskite structures. Alternative strontium‐free materials effectively address this issue, ensuring high performance and reliable operation during operational ...
Haewon Seo, Ji‐eun Won, Wooseok Lee, Haneul Choi, Sun‐Young Park, Younghun Shin, Insung Lee, Tae Jin Lim, Kyeounghak Kim, Jongsup Hong, Hye Jung Chang, Kyung Joong Yoon   +11 more
wiley   +1 more source

American Association of Poison Control Centers database characterization of human tilmicosin exposures, 2001–2005 [PDF]

, 2008
Jennifer A. Oakes, Steven A. Seifert
openalex   +1 more source