Response mechanism of hepatorenal metabolic barrier function to drugs and environmental poisons and intervention strategy of natural products. [PDF]
Front PharmacolLi Z, Li Y, Zhu J, Zheng Z, Xie W, Xu C.
europepmc +1 more source
Synthesis of functionalized polyolefins in a new continuous bench‐scale reactor apparatus
AIChE Journal, EarlyView.Abstract In‐reactor functionalized polyolefins (FPOs), produced by molecular catalysts, are a new class of polymer materials with applications ranging from high performance adhesives to bitumen compatibilization. In this work, we disclose a procedure for the synthesis of FPOs in a new Continuous Bench‐scale Reactor Apparatus (COBRA).
Miloud Bouyahyi +7 more
wiley +1 more source
Angewandte Chemie, EarlyView.A robust and efficient method to access diversely functionalized fluorinated piperidines was developed. The approach features the hydrogenation of polysubstituted pyridines bearing CF3, CF2H, and CF2CO2Et substituents using an inexpensive, readily available heterogeneous Pd/C catalyst under air‐ and moisture‐tolerant conditions, offering an appealing ...
Thibaud Charvillat +7 more
wiley +2 more sources
Unintentional paediatric paracetamol overdose: a retrospective observational study of dosing errors reported to an Australian Poisons Information Centre. [PDF]
BMC Public HealthChidiac AS +3 more
europepmc +1 more source
Porcine kidney xenotransplantation: From primate models to clinical reality
Animal Models and Experimental Medicine, EarlyView.In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo +3 more
wiley +1 more source
Entropy‐Stabilized Aluminate Catalysts That Break the Activity–Stability Tradeoff in CF4 Hydrolysis
Angewandte Chemie, EarlyView.Entropy‐stabilized aluminate breaks the activity–stability tradeoff in CF4 hydrolysis by combining a multication aluminate framework with an entropy‐stabilized lattice. An electron‐deficient Al–O environment is F‐philic but O‐phobic, enabling C–F activation while suppressing H2O poisoning. Under steam‐rich, strongly fluorinating conditions, the entropy‐
Seunghyuck Chi +7 more
wiley +2 more sources
Processing of DNA Topoisomerase II-DNA-Protein Crosslinks Associated With Anticancer Drugs. [PDF]
Genes CellsSakasai R, Iwabuchi K.
europepmc +1 more source
Angewandte Chemie, EarlyView.Heterogeneous iron‐catalyzed environmentally benign and sustainable CH‐oxidative esterification methodology has been developed for the synthesis of esters. This challenging reaction has been achieved by the rational design of specific single atom iron‐based catalyst with Fe‐N4 active centers, which empowered the oxidative esterification of methyl and ...
Zhuang Ma +8 more
wiley +2 more sources
A comprehensive overview of paracetamol poisoning admissions and long-term outcomes in New South Wales, Australia: a retrospective linked data cohort (PAVLOVA-3). [PDF]
Lancet Reg Health West PacChidiac AS +8 more
europepmc +1 more source